Sox2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:316817 Guerra GM, et al., Cell Type-Specific Role of RNA Nuclease SMG6 in Neurogenesis. Cells. 2021 Nov 30;10(12)
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7260257
Gene symbol:	Sox2
Gene name:	SRY (sex determining region Y)-box 2

Antibody:	Anti-Sox2 (ab97959)
Detection system:	Secondary antibody coupled to Cy3

Results

1A Ctr SOX2 ©

Specimen 1A Ctr: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: cerebral cortex ventricular layer	Present	Regionally restricted	1A Ctr SOX2	Expression is in neural progenitor cells.

Specimen 1A CNSdelta: embryonic day 14.5; Smg6^tm1.1Zqw/Smg6^tm1.2Zqw, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS22: cerebral cortex ventricular layer	Present		1A CNSdelta SOX2	Expression in this mutant is the same as in controls.

1F Ctr SOX2 ©

Specimen 1F Ctr: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebral cortex ventricular layer	Present	Regionally restricted	1F Ctr SOX2	Expression is in neural progenitor cells.

Specimen 1F CNSdelta: embryonic day 18.5; Smg6^tm1.1Zqw/Smg6^tm1.2Zqw, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: cerebral cortex ventricular layer	Present	Regionally restricted	1F CNSdelta SOX2	There is a significant decrease in the number of expressing cells in this mutant compared to controls.

4D Ctr SOX2 ©

Specimen 4D Ctr: embryonic day 18.5 (more

)
Note: Controls were littermates but their specific allelic background was not detailed.

Structure	Level	Pattern	Image	Note
TS26: cerebral cortex ventricular layer	Present	Regionally restricted	4D Ctr SOX2	Expression is in neural progenitor cells.

Specimen 4D CoHidelta: embryonic day 18.5; Emx1^tm1(cre)Krj/Emx1⁺, Smg6^tm1.1Zqw/Smg6^tm1.1Zqw (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: cerebral cortex ventricular layer	Present	Regionally restricted	4D CoHidelta SOX2	Expression in this mutant is the same as in controls.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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