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Gene Expression Data
Assay Details
Assay
Reference: J:111787 Gao F, et al., The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11987-92
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6860628
Gene symbol: Wt1
Gene name: WT1 transcription factor
Antibody: anti-WT1 (C-19; sc-192)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4c: embryonic day 13.5 (more )
Note: Littermates were used as controls, the exact genotype was not provided.
Structure Cell Type Level Pattern Image Note
TS21: Sertoli cell Sertoli cell Present 4c
Specimen 4f: embryonic day 13.5; Plekha5Tg(AMH-cre)1Flor/0, Wt1tm2Vih/Wt1tm1Jae (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS21: Sertoli cell Sertoli cell Present 4f The location and morphology of Sertoli cells is the same as in control embryos.
Specimen 4i: embryonic day 14.5 (more )
Note: Littermates were used as controls, the exact genotype was not provided.
Structure Cell Type Level Pattern Image Note
TS22: Sertoli cell Sertoli cell Present 4i
Specimen 4l: embryonic day 14.5; Plekha5Tg(AMH-cre)1Flor/0, Wt1tm2Vih/Wt1tm1Jae (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS22: Sertoli cell Sertoli cell Present 4l Sertoli cell nuclei in mutant testes were less rounded than those in control testes.
Specimen 5e: embryonic day 15.5 (more )
Note: Littermates were used as controls, the exact genotype was not provided.
Structure Cell Type Level Pattern Image Note
TS23: Sertoli cell Sertoli cell Present 5e
Specimen 5g: postnatal day 7 (more )
Note: Littermates were used as controls, the exact genotype was not provided.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 5g
Specimen 5o: embryonic day 15.5; Plekha5Tg(AMH-cre)1Flor/0, Wt1tm2Vih/Wt1tm1Jae (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS23: Sertoli cell Sertoli cell Present 5o In this mutant most of the Sertoli cells were scattered and outside of any discernible tubular structure.
Specimen 5p: embryonic day 15.5; Plekha5Tg(AMH-cre)1Flor/0, Wt1tm2Vih/Wt1tm1Jae (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS23: Sertoli cell Sertoli cell Present 5p In this mutant most of the Sertoli cells were scattered and outside of any discernible tubular structure.
Specimen 5q: postnatal day 7; Plekha5Tg(AMH-cre)1Flor/0, Wt1tm2Vih/Wt1tm1Jae (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present Single cells 5q In this mutant there were no positive Sertoli cells except in rare tubule remnants.
Specimen 5r: postnatal day 7; Plekha5Tg(AMH-cre)1Flor/0, Wt1tm2Vih/Wt1tm1Jae (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present Single cells 5r In this mutant there were no positive Sertoli cells except in rare tubule remnants.
Specimen 9a: embryonic day 15.5 (more )
Note: Littermates were used as controls, the exact genotype was not provided.
Structure Cell Type Level Pattern Image Note
TS23: Sertoli cell Sertoli cell Present 9a
Specimen 9b: embryonic day 15.5; Plekha5Tg(AMH-cre)1Flor/0, Wt1tm2Vih/Wt1tm1Jae (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS23: Sertoli cell Sertoli cell Present 9b In this mutant most of the Sertoli cells were scattered and outside of any discernible tubular structure.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory