Gene Expression Data
Assay Details
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Assay
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Reference:
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J:142507
Tian NM, et al., Foxg1 regulates retinal axon pathfinding by repressing an ipsilateral program in nasal retina and by causing optic chiasm cells to exert a net axonal growth-promoting activity. Development. 2008 Dec;135(24):4081-9
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:6842537
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Gene symbol:
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Foxg1
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Gene name:
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forkhead box G1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
1D:
embryonic day 14.5; Foxg1tm1M/Foxg1 +
(more )
Specimen
1D:
(close )
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Genetic Background:
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involves: 129S1/Sv * CBA
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Mutant Allele(s):
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Foxg1tm1M/Foxg1+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: retina |
Present |
Regionally restricted |
1D
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Expression mainly in nasal retina.
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Specimen
1E:
embryonic day 14.5; Foxg1tm1M/Foxg1 +
(more )
Specimen
1E:
(close )
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Genetic Background:
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involves: 129S1/Sv * CBA
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Mutant Allele(s):
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Foxg1tm1M/Foxg1+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: retina |
Present |
Regionally restricted |
1E
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In dorsal retina, widespread expression throughout all layers of nasal and temporal retina.
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Specimen
1F:
embryonic day 14.5; Foxg1tm1M/Foxg1 +
(more )
Specimen
1F:
(close )
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Genetic Background:
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involves: 129S1/Sv * CBA
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Mutant Allele(s):
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Foxg1tm1M/Foxg1+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: retina |
Present |
Regionally restricted |
1F
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Moving from dorsal to central sections, expression throughout nasal retina; occupies progressively less of temporal retina.
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Specimen
1G:
embryonic day 14.5; Foxg1tm1M/Foxg1 +
(more )
Specimen
1G:
(close )
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Genetic Background:
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involves: 129S1/Sv * CBA
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Mutant Allele(s):
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Foxg1tm1M/Foxg1+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: retina |
Present |
Regionally restricted |
1G
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Moving from dorsal to central sections, expression throughout nasal retina; occupies progressively less of temporal retina.
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Specimen
1H:
embryonic day 14.5; Foxg1tm1M/Foxg1 +
(more )
Specimen
1H:
(close )
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Genetic Background:
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involves: 129S1/Sv * CBA
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Mutant Allele(s):
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Foxg1tm1M/Foxg1+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: retina |
Present |
Regionally restricted |
1H
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Moving from dorsal to central sections, expression throughout nasal retina; occupies progressively less of temporal retina.
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Specimen
1I:
embryonic day 14.5; Foxg1tm1M/Foxg1 +
(more )
Specimen
1I:
(close )
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Genetic Background:
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involves: 129S1/Sv * CBA
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Mutant Allele(s):
|
Foxg1tm1M/Foxg1+
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
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Not Specified
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Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: retina |
Present |
Regionally restricted |
1I
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Moving through ventral sections, expression in smaller part of nasal retina
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Specimen
1J:
embryonic day 14.5; Foxg1tm1M/Foxg1 +
(more )
Specimen
1J:
(close )
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Genetic Background:
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involves: 129S1/Sv * CBA
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Mutant Allele(s):
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Foxg1tm1M/Foxg1+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: retina |
Present |
Regionally restricted |
1J
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Expression increasingly restricted to anterior-most region of nasal retina.
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Specimen
1K:
embryonic day 14.5; Foxg1tm1M/Foxg1 +
(more )
Specimen
1K:
(close )
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Genetic Background:
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involves: 129S1/Sv * CBA
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Mutant Allele(s):
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Foxg1tm1M/Foxg1+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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|
Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: retina |
Present |
Regionally restricted |
1K
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Expresssion absent in ventral-most section.
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Specimen
E13.5 not shown:
embryonic day 13.5; Foxg1tm1M/Foxg1 +
(more )
Specimen
E13.5 not shown:
(close )
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Genetic Background:
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involves: 129S1/Sv * CBA
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Mutant Allele(s):
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Foxg1tm1M/Foxg1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: retina |
Present |
Regionally restricted |
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Authors state results were the same at E13.5 and E15.5 as seen at E14.5.
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Specimen
E15.5 not shown:
embryonic day 15.5; Foxg1tm1M/Foxg1 +
(more )
Specimen
E15.5 not shown:
(close )
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Genetic Background:
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involves: 129S1/Sv * CBA
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Mutant Allele(s):
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Foxg1tm1M/Foxg1+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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|
Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: retina |
Present |
Regionally restricted |
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Authors state results were the same at E13.5 and E15.5 as seen at E14.5.
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