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Gene Expression Data
Assay Details
Assay
Reference: J:241009 Himmelstein DS, et al., SHH E176/E177-Zn2+ conformation is required for signaling at endogenous sites. Dev Biol. 2017 Apr 15;424(2):221-235
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6761580
Gene symbol: Ptch1
Gene name: patched 1
Reporter: lacZ
Direct Detection
Results
Specimen 5C Ptc1+/-: embryonic day 9.5; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS15: future spinal cord Present 5C left
Specimen 5C Ptc1+/- E177A/-: embryonic day 9.5; Ptch1tm1Mps/Ptch1+, Shhtm1.1Jhdk/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS15: future spinal cord Absent 5C middle
Specimen 5C Ptc1+/- Shh-/-: embryonic day 9.5; Ptch1tm1Mps/Ptch1+, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS15: future spinal cord Absent 5C right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory