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Gene Expression Data
Assay Details
Assay
Reference: J:308866 Mase S, et al., Notch1 and Notch2 collaboratively maintain radial glial cells in mouse neurogenesis. Neurosci Res. 2021 Sep;170:122-132
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6755501
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki-67 (SP6; MA5-14520, RM-9106; ab16667)
Detection system: Alexa Fluor 680
Results
Specimen 2A Notch1+/D Notch2+/D: embryonic day 11.5; Emx1tm1(cre)Yql/Emx1+, Notch1tm2Rko/Notch1+, Notch2tm3Grid/Notch2+ (more )
Note: Conditional mutant. Double labeled: magenta - Mki67; green - EdU.
Structure Level Pattern Image Note
TS19: telencephalon Present 2A Notch1+/D Notch2+/D Ki67 , 2A Notch1+/D Notch2+/D merge
Specimen 2A Notch1D/D: embryonic day 11.5; Emx1tm1(cre)Yql/Emx1+, Notch1tm2Rko/Notch1tm2Rko (more )
Note: Conditional mutant. Double labeled: magenta - Mki67; green - EdU.
Structure Level Pattern Image Note
TS19: telencephalon Present 2A Notch1D/D Ki67 , 2A Notch1D/D merge Authors report severe increase in cell cycle exit compared to double heterozygotes.
Specimen 2A Notch2D/D: embryonic day 11.5; Emx1tm1(cre)Yql/Emx1+, Notch2tm3Grid/Notch2tm3Grid (more )
Note: Conditional mutant. Double labeled: magenta - Mki67; green - EdU.
Structure Level Pattern Image Note
TS19: telencephalon Present 2A Notch2D/D merge , 2A Notch2D/D Ki67
Specimen 2A Notch1D/D Notch2D/D: embryonic day 11.5; Emx1tm1(cre)Yql/Emx1+, Notch1tm2Rko/Notch1tm2Rko, Notch2tm3Grid/Notch2tm3Grid (more )
Note: Conditional mutant. Double labeled: magenta - Mki67; green - EdU.
Structure Level Pattern Image Note
TS19: telencephalon Present 2A Notch1D/D Notch2D/D merge , 2A Notch1D/D Notch2D/D Ki67 Authors report severe increase in cell cycle exit compared to double heterozygotes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
MGI 6.24 		The Jackson Laboratory