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Gene Expression Data
Assay Details
Assay
Reference: J:293298 Zhang M, et al., Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development. Theranostics. 2019;9(17):5065-5084
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6711416
Gene symbol: Cdc42
Gene name: cell division cycle 42
Antibody: anti-Cdc42
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen S1C WT E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: epidermis Present S1C upper left
Specimen S1C KO E15.5: embryonic day 15.5; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: epidermis Present S1C lower left Reduced expression compared with the wild-type.
Specimen S1C WT E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epidermis Present S1C upper middle
Specimen S1C KO E17.5: embryonic day 17.5; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: epidermis Weak S1C lower middle Significantly reduced expression compared with the wild-type.
Specimen S1C WT P1: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: epidermis Present S1C upper right
Specimen S1C KO P1: postnatal day 1; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: epidermis Absent S1C lower right
Specimen S1E WT Stomach: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: stomach Present S1E1-1
Specimen S1E KO Stomach: postnatal day 1; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: stomach Present S1E2-1 Similar as in the wild-type.
Specimen S1E WT Intestine: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: intestine Present S1E1-2
Specimen S1E KO Intestine: postnatal day 1; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: intestine Present S1E2-2 Similar as in the wild-type.
Specimen S1E WT Lung: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: lung Present S1E1-3
Specimen S1E KO Lung: postnatal day 1; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: lung Present S1E2-3 Similar as in the wild-type.
Specimen S1E WT Liver: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: liver Present S1E1-4
Specimen S1E KO Liver: postnatal day 1; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: liver Present S1E2-4 Similar as in the wild-type.
Specimen S1E WT Heart: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: heart Present S1E1-5
Specimen S1E KO Heart: postnatal day 1; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: heart Present S1E2-5 Similar as in the wild-type.
Specimen S1E WT Esophagus: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: esophagus epithelium Present S1E1-6
Specimen S1E KO Esophagus: postnatal day 1; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: esophagus epithelium Absent S1E2-6 Similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory