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Gene Expression Data
Assay Details
Assay
Reference: J:291094 Sheikh BN, et al., Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nat Cell Biol. 2020 Jul;22(7):828-841
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6511314
Gene symbol: Satb2
Gene name: special AT-rich sequence binding protein 2
Antibody: anti-SATB2 (SATBA4B10; ab51502)
Detection system: Alexa Fluor 488
Results
Specimen S2c Nes-Cre T/+: embryonic day 14.5; Tg(Nes-cre)1Kln/0 (more )
Note: Multi-labeled: green - Satb2; white - Casp3 (assay MGI:6511312); red - CTIP2 (Bcl11b assay MGI:6511313); blue - DAPI.
Structure Level Pattern Image Note
TS22: cerebral cortex Present S2c Nes-Cre T/+

Specimen S2c Nes-Cre T/+ inset: embryonic day 14.5; Tg(Nes-cre)1Kln/0 (more )
Note: Multi-labeled: green - Satb2; white - Casp3 (assay MGI:6511312); red - CTIP2 (Bcl11b assay MGI:6511313); blue - DAPI.
Structure Level Pattern Image Note
TS22: cerebral cortex Present S2c Nes-Cre T/+ inset

Specimen S2c Mof nKO: embryonic day 14.5; Kat8tm1.2Avo/Kat8tm1.2Avo, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Multi-labeled: green - Satb2; white - Casp3 (assay MGI:6511312); red - CTIP2 (Bcl11b assay MGI:6511313); blue - DAPI.
Structure Level Pattern Image Note
TS22: cerebral cortex Present S2c Mof nKO Authors report normal layering at E14.5.

Specimen S2c Mof nKO inset: embryonic day 14.5; Kat8tm1.2Avo/Kat8tm1.2Avo, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Triple labeled: green - Satb2; red - CTIP2 (Bcl11b assay MGI:6511313); blue - DAPI.
Structure Level Pattern Image Note
TS22: cerebral cortex Present S2c Mof nKO inset Authors report normal layering at E14.5.

Specimen S2d Mof fl/fl: embryonic day 16.5; Kat8tm1.2Avo/Kat8tm1.2Avo (more )
Note: Triple labeled: green - Satb2; red - CTIP2 (Bcl11b assay MGI:6511313); blue - DAPI.
Structure Level Pattern Image Note
TS24: cerebral cortex Present S2d Mof fl/fl

Specimen S2d Mof nKO: embryonic day 16.5; Kat8tm1.2Avo/Kat8tm1.2Avo, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Triple labeled: green - Satb2; red - CTIP2 (Bcl11b assay MGI:6511313); blue - DAPI.
Structure Level Pattern Image Note
TS24: cerebral cortex Present Regionally restricted S2d Mof nKO Authors report cortex was severely disorganized at E16.5.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory