About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:291094 Sheikh BN, et al., Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nat Cell Biol. 2020 Jul;22(7):828-841
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6511312
Gene symbol: Casp3
Gene name: caspase 3
Results
Specimen S2c Nes-Cre T/+: embryonic day 14.5; Tg(Nes-cre)1Kln/0 (more )
Note: Multi-labeled: white - Casp3; red - Bcl11b (CTIP2; assay MGI:6511313); green - Satb2 (assay MGI:6511314); blue - DAPI.
Structure Level Pattern Image Note
TS22: cerebral cortex Absent S2c Nes-Cre T/+
Specimen S2c Nes-Cre T/+ inset: embryonic day 14.5; Tg(Nes-cre)1Kln/0 (more )
Note: Multi-labeled: white - Casp3; red - Bcl11b (CTIP2; assay MGI:6511313); green - Satb2 (assay MGI:6511314); blue - DAPI.
Structure Level Pattern Image Note
TS22: cerebral cortex Absent S2c Nes-Cre T/+ inset
Specimen S2c Mof nKO: embryonic day 14.5; Kat8tm1.2Avo/Kat8tm1.2Avo, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Multi-labeled: white - Casp3; red - Bcl11b (CTIP2; assay MGI:6511313); green - Satb2 (assay MGI:6511314); blue - DAPI.
Structure Level Pattern Image Note
TS22: cerebral cortex Absent S2c Mof nKO No significant cell death in developing Mof nKO cortex at E14.5
Specimen S2c Mof nKO inset: embryonic day 14.5; Kat8tm1.2Avo/Kat8tm1.2Avo, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Multi-labeled: white - Casp3; red - Bcl11b (CTIP2; assay MGI:6511313); green - Satb2 (assay MGI:6511314); blue - DAPI.
Structure Level Pattern Image Note
TS22: cerebral cortex Absent S2c Mof nKO inset No significant cell death in developing Mof nKO cortex at E14.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory