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Gene Expression Data
Assay Details
Assay
Reference: J:245204 Rashid M, et al., Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation. Development. 2017 Nov 01;144(21):4002-4014
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6509620
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Antibody: Anti-Tbr1 (AB2261)
Detection system: Secondary antibody
Results
Specimen S1C PxnF/+: postnatal day 1; Pxntm1.1Cet/Pxn+ (more )
Structure Level Pattern Image Note
TS27: cortical layer V Present S1C PxnF/+
TS27: cortical layer VI Present S1C PxnF/+

Specimen S1C Nes-Cre:PxnF/F: postnatal day 1; Pxntm1.1Cet/Pxntm1.1Cet, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: cortical layer V Present S1C Nes-Cre:PxnF/F Expression in this mutant is the same as in controls.
TS27: cortical layer VI Present S1C Nes-Cre:PxnF/F Expression in this mutant is the same as in controls.

Specimen S1D PxnF/FHic-5-/-: postnatal day 0; Pxntm1.1Cet/Pxntm1.1Cet, Tgfb1i1tm1.2Cet/Tgfb1i1tm1.2Cet (more )
Structure Level Pattern Image Note
TS27: cortical layer V Present S1D PxnF/FHic-5-/- Expression in this mutant is the same as in controls.
TS27: cortical layer VI Present S1D PxnF/FHic-5-/- Expression in this mutant is the same as in controls.

Specimen S1D Nes-Cre:PxnF/F:Hic-5-/-: postnatal day 0; Pxntm1.1Cet/Pxntm1.1Cet, Tgfb1i1tm1.2Cet/Tgfb1i1tm1.2Cet, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: cortical layer V Present S1D Nes-Cre:PxnF/FHic-5-/- Expression in this mutant is the same as in controls.
TS27: cortical layer VI Present S1D Nes-Cre:PxnF/FHic-5-/- Expression in this mutant is the same as in controls.

Specimen S1E PxnF/F: postnatal day 1; Pxntm1.1Cet/Pxntm1.1Cet (more )
Structure Level Pattern Image Note
TS27: cortical layer V Present S1E PxnF/F
TS27: cortical layer VI Present S1E PxnF/F

Specimen S1E NEX-Cre:PxnF/F: postnatal day 1; Neurod6tm1(cre)Kan/Neurod6+, Pxntm1.1Cet/Pxntm1.1Cet (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: cortical layer V Present S1E NEX-Cre:PxnF/F Expression in this mutant is the same as in controls.
TS27: cortical layer VI Present S1E NEX-Cre:PxnF/F Expression in this mutant is the same as in controls.

Specimen S1F PxnF/+: postnatal day 35; Pxntm1.1Cet/Pxn+ (more )
Structure Level Pattern Image Note
TS28: cortical layer V Present S1F PxnF/+
TS28: cortical layer VI Present S1F PxnF/+

Specimen S1F Nes-Cre:PxnF/F: postnatal day 35; Pxntm1.1Cet/Pxntm1.1Cet, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cortical layer V Present S1F Nes-Cre:PxnF/F Expression in this mutant is the same as in controls.
TS28: cortical layer VI Present S1F Nes-Cre:PxnF/F Expression in this mutant is the same as in controls.

Specimen S1G PxnF/F:Hic-5-/-: postnatal day 35; Pxntm1.1Cet/Pxntm1.1Cet, Tgfb1i1tm1.2Cet/Tgfb1i1tm1.2Cet (more )
Structure Level Pattern Image Note
TS28: cortical layer V Present S1G PxnF/FHic-5-/-
TS28: cortical layer VI Present S1G PxnF/FHic-5-/-

Specimen S1G Nes-Cre:PxnF/F:Hic-5-/-: postnatal day 35; Pxntm1.1Cet/Pxntm1.1Cet, Tgfb1i1tm1.2Cet/Tgfb1i1tm1.2Cet, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cortical layer V Present S1G Nes-Cre:PxnF/FHic-5-/- Expression in this mutant is the same as in controls.
TS28: cortical layer VI Present S1G Nes-Cre:PxnF/FHic-5-/- Expression in this mutant is the same as in controls.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory