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Gene Expression Data
Assay Details
Assay
Reference: J:297493 Matos-Rodrigues GE, et al., Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome. Dis Model Mech. 2020 Oct 30;13(10):dmm045807
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6506438
Gene symbol: Rcvrn
Gene name: recoverin
Antibody: Anti-Recoverin (AB5585)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to Cy3
Results
Specimen 3E AtripCtrl: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer Present Regionally restricted 3E AtripCtrl Expression was detected in rod and cone photoreceptors.
Specimen 3E Atripalpha-Cre: postnatal day 21; Atriptm1.1Pof/Atriptm1.1Pof, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 3E Atripalpha-Cre Displaced immunopositive rosettes were observed in the mutant.
Specimen 5E AtripCtrl: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer Present Regionally restricted 5E AtripCtrl Expression was detected in rod and cone photoreceptors.
Specimen 5E Atripalpha-Cre: postnatal day 30; Atriptm1.1Pof/Atriptm1.1Pof, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 5E Atripalpha-Cre Displaced immunopositive rosettes were observed in the mutant.
Specimen 5E Atripalpha-Cre;Trp53-/-: postnatal day 30; Atriptm1.1Pof/Atriptm1.1Pof, Tg(Pax6-cre,GFP)2Pgr/0, Trp53tm1Tyj/Trp53tm1Tyj (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 5E Atripalpha-Cre;Trp53-/- Double-knockout retinas displayed normal physiology, lamination and an intact outer nuclear layer.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory