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Gene Expression Data
Assay Details
Assay
Reference: J:160146 Rowan S, et al., Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity. Genes Dev. 2010 May 15;24(10):980-5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6502091
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6
Detection system: Alexa Fluor 488
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Anti-Pax6 MGI:6502083 may have been used in this assay.
Results
Specimen S1 Prep1+/+ Pax6: embryonic day 9.5 (more )
Note: Double labeled: green - Pax6; red - Prep1 (Pknox1 assay MGI:6502092).
Structure Level Pattern Image Note
TS15: lens pre-placode Present Regionally restricted S1_Prep1+/+ Prep1/Pax6 Expression in presumptive lens epithelium.
Specimen S1 Prep1i/- Pax6: embryonic day 9.5; Pknox1Gt(OST71835)Lex/Pknox1tm1Ngc (more )
Note: Double labeled: green - Pax6; red - Prep1 (Pknox1 assay MGI:6502092).
Structure Level Pattern Image Note
TS15: lens primordium Present Regionally restricted S1_Prep1i/- Prep1/Pax6 Initially expressed in presumptive lens epithelium.
Specimen S2 Pax6+/+ Pax6: embryonic day 9.25 (more )
Note: 16 somites
Structure Level Pattern Image Note
TS14: lens pre-placode Present Regionally restricted S2_Pax6+/+ Pax6 Expression in presumptive lens epithelium.
Specimen S2 Sey-Neu Pax6: embryonic day 9.25; Pax6Sey-Neu/Pax6Sey-Neu (more )
Note: 16 somites
Structure Level Pattern Image Note
TS14: lens primordium Absent S2_Pax6Sey-Neu Pax6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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