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Gene Expression Data
Assay Details
Assay
Reference: J:160146 Rowan S, et al., Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity. Genes Dev. 2010 May 15;24(10):980-5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6502092
Gene symbol: Pknox1
Gene name: Pbx/knotted 1 homeobox
Antibody: anti-Prep1
Detection system: Cy3
Results
Specimen S1 Prep1+/+ Prep1: embryonic day 9.5 (more )
Note: Double labeled: red - Prep1 (Pknox1); green - Pax6 (assay MGI:6502091).
Structure Level Pattern Image Note
TS15: eye Present Ubiquitous S1_Prep1+/+ Prep1/Pax6 , S1_Prep1+/+ Prep1/DAPI Ubiquitous expressin in eye region and largely, but not exclusively, nuclear.
Specimen S1 Prep1i/- Prep1: embryonic day 9.5; Pknox1Gt(OST71835)Lex/Pknox1tm1Ngc (more )
Note: Double labeled: red - Prep1 (Pknox1); green - Pax6 (assay MGI:6502091).
Structure Level Pattern Image Note
TS15: eye Absent S1_Prep1i/- Prep1/DAPI , S1_Prep1i/- Prep1/Pax6 Expression largely undetectable.
Specimen S2 Pax6+/+ Prep1: embryonic day 9.25 (more )
Note: 16 somites
Structure Level Pattern Image Note
TS14: eye Present Regionally restricted S2_Pax6+/+ Prep1 Expression was both nuclear and cytoplasmic.
Specimen S2 Sey-Neu Prep1: embryonic day 9.25; Pax6Sey-Neu/Pax6Sey-Neu (more )
Note: 16 somites
Structure Level Pattern Image Note
TS14: eye Present Regionally restricted S2_Pax6Sey-Neu Prep1 Authors report expression does not depend on Pax6 expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory