Gene Expression Data
Assay Details
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Assay
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Reference:
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J:80423
Paratore C, et al., Sox10 haploinsufficiency affects maintenance of progenitor cells in a mouse model of Hirschsprung disease. Hum Mol Genet. 2002 Nov 15;11(24):3075-85
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6451431
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Gene symbol:
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Sox10
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Gene name:
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SRY (sex determining region Y)-box 10
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Probe:
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Sox10 probe23
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
2A:
embryonic day 13.0
(more  )
Specimen
2A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 13.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
2B:
embryonic day 13.0; Sox10tm1Weg/Sox10 +
(more )
Specimen
2B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C3HeB/FeJ * C57BL/6J
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Mutant Allele(s):
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Sox10tm1Weg/Sox10+
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Age:
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embryonic day 13.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
2C:
embryonic day 13.0
(more )
Specimen
2C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 13.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: enteric nervous system |
Present |
Regionally restricted |
2C
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Expression is in the myenteric plexus of the proximal gut.
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| TS21: hindgut |
Present |
Regionally restricted |
2C
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Expression is in the myenteric plexus of the proximal gut.
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| TS21: midgut |
Present |
Regionally restricted |
2C
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Expression is in the myenteric plexus of the proximal gut.
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Specimen
2D:
embryonic day 13.0; Sox10tm1Weg/Sox10 +
(more )
Specimen
2D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C3HeB/FeJ * C57BL/6J
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Mutant Allele(s):
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Sox10tm1Weg/Sox10+
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Age:
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embryonic day 13.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
5A:
embryonic day 13.0
(more )
Specimen
5A:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 13.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
5B:
embryonic day 13.0; Sox10tm1Weg/Sox10 +
(more )
Specimen
5B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C3HeB/FeJ * C57BL/6J
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Mutant Allele(s):
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Sox10tm1Weg/Sox10+
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Age:
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embryonic day 13.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: midgut |
Weak |
Single cells |
5B
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Specimen
5D:
embryonic day 15.0
(more )
Specimen
5D:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
5E:
embryonic day 15.0; Sox10tm1Weg/Sox10 +
(more )
Specimen
5E:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C3HeB/FeJ * C57BL/6J
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Mutant Allele(s):
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Sox10tm1Weg/Sox10+
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Age:
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embryonic day 15.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: gut |
Present |
Regionally restricted |
5E
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Expression is in the more proximal regions of the gut.
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| TS23: midgut |
Absent |
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5E
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Analysis Tools