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Gene Expression Data
Assay Details
Assay
Reference: J:127471 Wang S, et al., Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse. Mech Dev. 2007 Nov-Dec;124(11-12):898-910
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6449812
Gene symbol: Neurog3
Gene name: neurogenin 3
Antibody: anti-Ngn3
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Anti-Ngn3 MGI:6449785 may have been used in this assay.
Results
Specimen 2 E10.5: embryonic day 10.5 (more )
Note: Double labeled: green - Neurog3; red - Myt1 (assay MGI:6449800).
Structure Level Pattern Image Note
TS17: pancreas primordium Present 2_E10.5 Ngn3 , 2_E10.5 Merge Expression detectable at E10.5.
Specimen 2 E13.5: embryonic day 13.5 (more )
Note: Double labeled: green - Neurog3; red - Myt1 (assay MGI:6449800).
Structure Level Pattern Image Note
TS21: pancreas Present 2_E13.5 Merge , 2_E13.5 Ngn3
Specimen 2 E15.5: embryonic day 15.5 (more )
Note: Double labeled: green - Neurog3; red - Myt1 (assay MGI:6449800).
Structure Level Pattern Image Note
TS23: pancreas Strong 2_E15.5 Ngn3 , 2_E15.5 Merge Expression peaks at E15.5.
Specimen postnatal not shown: postnatal (more )
Structure Level Pattern Image Note
TS28: pancreas Absent
Specimen S4 E10.5 +/+: embryonic day 10.5 (more )
Note: Double labeled: green - Neurog3; red - Pdx1 (assay MGI:6449807).
Structure Level Pattern Image Note
TS17: pancreas primordium Present S4A E10.5 +/+ Number of expressing cells, as well as expression levels within individual cells, did not vary between genotypes.
Specimen S4 E10.5 +/-: embryonic day 10.5; Myt1tm1.1Ggu/Myt1+ (more )
Note: Double labeled: green - Neurog3; red - Pdx1 (assay MGI:6449807).
Structure Level Pattern Image Note
TS17: pancreas primordium Present S4A E10.5 +/- Number of expressing cells, as well as expression levels within individual cells, did not vary between genotypes.
Specimen S4 E10.5 -/-: embryonic day 10.5; Myt1tm1.1Ggu/Myt1tm1.1Ggu (more )
Note: Double labeled: green - Neurog3; red - Pdx1 (assay MGI:6449807).
Structure Level Pattern Image Note
TS17: pancreas primordium Present S4A E10.5 -/- Number of expressing cells, as well as expression levels within individual cells, did not vary between genotypes.
Specimen S4 E13.5 +/+: embryonic day 13.5 (more )
Note: Double labeled: green - Neurog3; red - Pdx1 (assay MGI:6449807).
Structure Level Pattern Image Note
TS21: pancreas Present S4A E13.5 +/+ Number of expressing cells, as well as expression levels within individual cells, did not vary between genotypes.
Specimen S4 E13.5 +/-: embryonic day 13.5; Myt1tm1.1Ggu/Myt1+ (more )
Note: Double labeled: green - Neurog3; red - Pdx1 (assay MGI:6449807).
Structure Level Pattern Image Note
TS21: pancreas Present S4A E13.5 +/- Number of expressing cells, as well as expression levels within individual cells, did not vary between genotypes.
Specimen S4 E13.5 -/-: embryonic day 13.5; Myt1tm1.1Ggu/Myt1tm1.1Ggu (more )
Note: Double labeled: green - Neurog3; red - Pdx1 (assay MGI:6449807).
Structure Level Pattern Image Note
TS21: pancreas Present S4A E13.5 -/- Number of expressing cells, as well as expression levels within individual cells, did not vary between genotypes.
Specimen S4 E15.5 +/+: embryonic day 15.5 (more )
Note: Double labeled: green - Neurog3; red - Amy (assay MGI:6449811).
Structure Level Pattern Image Note
TS23: pancreas Present S4A E15.5 +/+ Number of expressing cells, as well as expression levels within individual cells, did not vary between genotypes.
Specimen S4 E15.5 +/-: embryonic day 15.5; Myt1tm1.1Ggu/Myt1+ (more )
Note: Double labeled: green - Neurog3; red - Amy (assay MGI:6449811).
Structure Level Pattern Image Note
TS23: pancreas Present S4A E15.5 +/- Number of expressing cells, as well as expression levels within individual cells, did not vary between genotypes.
Specimen S4 E15.5 -/-: embryonic day 15.5; Myt1tm1.1Ggu/Myt1tm1.1Ggu (more )
Note: Double labeled: green - Neurog3; red - Amy (assay MGI:6449811).
Structure Level Pattern Image Note
TS23: pancreas Present S4A E15.5 -/- Number of expressing cells, as well as expression levels within individual cells, did not vary between genotypes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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