About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:186556 Trask MC, et al., Yin-Yang1 is required for epithelial-to-mesenchymal transition and regulation of Nodal signaling during mammalian gastrulation. Dev Biol. 2012 Aug 15;368(2):273-82
Assay type: RNA in situ
MGI Accession ID: MGI:6446831
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Probe: Otx2 probe46
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4C: embryonic day 7.0 (more )
Note: littermate control; exact genotype not specified
Structure Level Pattern Image Note
TS10: neural ectoderm Present 4C
Specimen 4D: embryonic day 7.5 (more )
Note: littermate control; exact genotype not specified
Structure Level Pattern Image Note
TS11: neural ectoderm Present 4D
Specimen 4H: embryonic day 7.0; Yy1tm1Yshi/Yy1tm2.1Yshi, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS10: embryo ectoderm Present Regionally restricted 4H The expression domain is reduced in the mutant relative to wild type and fails to become anteriorly restricted.
Specimen 4I: embryonic day 7.5; Yy1tm1Yshi/Yy1tm2.1Yshi, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: embryo Present Regionally restricted 4I In the mutant expression is confined to a small population of distal epiblast cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory