Yy1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:186556 Trask MC, et al., Yin-Yang1 is required for epithelial-to-mesenchymal transition and regulation of Nodal signaling during mammalian gastrulation. Dev Biol. 2012 Aug 15;368(2):273-82
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6446807
Gene symbol:	Yy1
Gene name:	YY1 transcription factor

Antibody:	anti-YY1 (H-414; sc-1703)
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

1A ©

Specimen 1A: embryonic day 5.5 (more

)
Note: littermate control; exact genotype not specified

Structure	Level	Pattern	Image	Note
TS7: epiblast	Present	Ubiquitous	1A

1B ©

Specimen 1B: embryonic day 6.5 (more

)
Note: littermate control; exact genotype not specified

Structure	Level	Pattern	Image	Note
TS9: embryo	Present	Ubiquitous	1B
TS9: primitive endoderm	Present		1B	Expression is seen in the visceral endoderm.

1C ©

Specimen 1C: embryonic day 6.5 (more

)
Note: littermate control; exact genotype not specified

Structure	Level	Pattern	Image	Note
TS9: extraembryonic component	Present	Ubiquitous	1C

1D ©

Specimen 1D: embryonic day 5.5; Yy1^tm1Yshi/Yy1^tm2.1Yshi, Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS7: epiblast	Present	Ubiquitous	1D	Expression is as in wild type.

1E ©

Specimen 1E: embryonic day 6.5; Yy1^tm1Yshi/Yy1^tm2.1Yshi, Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS9: embryo	Absent		1E	Expression is lost in the epiblast.
TS9: primitive endoderm	Present		1E	Expression is maintained in the visceral endoderm.

1F ©

Specimen 1F: embryonic day 6.5; Yy1^tm1Yshi/Yy1^tm2.1Yshi, Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS9: extraembryonic component	Present	Ubiquitous	1F

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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