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Gene Expression Data
Assay Details
Assay
Reference: J:93163 Boulet AM, et al., The roles of Fgf4 and Fgf8 in limb bud initiation and outgrowth. Dev Biol. 2004 Sep 15;273(2):361-72
Assay type: RNA in situ
MGI Accession ID: MGI:6423495
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe172
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 6I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present 6I
Specimen 6J: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 6J
TS19: hindlimb bud Present 6J
Specimen 6K: embryonic day 10.5; Fgf4tm1Mrc/Fgf4tm1Mrc, Fgf8tm2Mrc/Fgf8tm2Mrc, Tg(Rarb-cre)1Mrc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud Trace 6K Expression barely detectable.
Specimen 6L: embryonic day 11.5; Fgf4tm1Mrc/Fgf4tm1Mrc, Fgf8tm2Mrc/Fgf8tm2Mrc, Tg(Rarb-cre)1Mrc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Absent 6L
TS19: hindlimb bud Present 6L
Specimen 6M: embryonic day 10.5; Fgf4tm1Mrc/Fgf4tm1Mrc, Fgf8tm2Mrc/Fgf8tm2Mrc, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud Present 6M
Specimen 6N: embryonic day 11.5; Fgf4tm1Mrc/Fgf4tm1Mrc, Fgf8tm2Mrc/Fgf8tm2Mrc, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud Absent 6N Expression essentially absent.
TS19: hindlimb bud Absent 6N Expression essentially absent.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory