Col4a1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:271730 Kask K, et al., Targeted deletion of RIC8A in mouse neural precursor cells interferes with the development of the brain, eyes, and muscles. Dev Neurobiol. 2018 Apr;78(4):374-390
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6416431
Gene symbol:	Col4a1
Gene name:	collagen, type IV, alpha 1

Antibody:	anti-Collagen IV (ab6586)
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

Specimen S4C: embryonic day 14.5 (more

)
Note: Littermate control; the genotype was either NestinCre+/-Ric8a+/^tm2.1Aks, NestinCre-/-;Ric8a^tm1Aks/^tm2.1Aks, or NestinCre-/-; Ric8a+/^tm2.1Aks.

Structure	Level	Pattern	Image	Note
TS22: neocortex	Present		S4D , S4C

Specimen S4C': embryonic day 14.5; Ric8a^tm1Aks/Ric8a^tm2.1Aks, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS22: neocortex	Present	Regionally restricted	S4D' , S4C'	Expression is non-continuous and interrupted in this mutant in the areas with ectopias.

Specimen not shown: embryonic day 14.5 (more

)
Note: Littermate control; the genotype was either NestinCre+/-Ric8a+/^tm2.1Aks, NestinCre-/-;Ric8a^tm1Aks/^tm2.1Aks, or NestinCre-/-; Ric8a+/^tm2.1Aks.

Structure	Level	Pattern	Image	Note
TS22: lateral ganglionic eminence	Present

Specimen not shown CKO: embryonic day 14.5; Ric8a^tm1Aks/Ric8a^tm2.1Aks, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS22: lateral ganglionic eminence	Weak

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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