Dag1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:271730 Kask K, et al., Targeted deletion of RIC8A in mouse neural precursor cells interferes with the development of the brain, eyes, and muscles. Dev Neurobiol. 2018 Apr;78(4):374-390
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6416430
Gene symbol:	Dag1
Gene name:	dystroglycan 1

Antibody:	anti-alpha-Dystroglycan (IIH6C4, 05-593)
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

Specimen S4A: embryonic day 15.5 (more

)
Note: Littermate control; the genotype was either NestinCre+/-Ric8a+/^tm2.1Aks, NestinCre-/-;Ric8a^tm1Aks/^tm2.1Aks, or NestinCre-/-; Ric8a+/^tm2.1Aks.

Structure	Level	Pattern	Image	Note
TS23: cerebral cortex	Present	Regionally restricted	S4A , S4B	Expression is in the endfeet of radial glial cells.
TS23: telencephalon meninges	Present		S4B , S4A

Specimen S4A': embryonic day 15.5; Ric8a^tm1Aks/Ric8a^tm2.1Aks, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS23: cerebral cortex	Present	Regionally restricted	S4A' , S4B'	Expression is discontinuous in this mutant.
TS23: telencephalon meninges	Present	Regionally restricted	S4A' , S4B'	Expression is discontinuous in this mutant.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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