Bmp4 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:150759 Lallemand Y, et al., Msx genes are important apoptosis effectors downstream of the Shh/Gli3 pathway in the limb. Dev Biol. 2009 Jul 15;331(2):189-98
Assay type:	RNA in situ
MGI Accession ID:	MGI:6404395
Gene symbol:	Bmp4
Gene name:	bone morphogenetic protein 4

Probe:

Bmp4 probe86

Results

Specimen 5B Forelimb Control: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: forelimb bud	Present	Regionally restricted	5B FL Control

5B FL Shh-/- ©

Specimen 5B Forelimb Shh-/-: embryonic day 11.5; Shh^tm1Amc/Shh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS19: forelimb bud	Present	Regionally restricted	5B FL Shh-/-	Expression comparable to that of controls, but not as polarized.

Specimen 5B Forelimb Shh-/-Msx1-/-Msx2+/-: embryonic day 11.5; Msx1^tm1Bero/Msx1^tm1Bero, Msx2^tm1Bero/Msx2⁺, Shh^tm1Amc/Shh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS19: forelimb bud	Present	Regionally restricted	5B FL Shh-/- Msx1-/- Msx2+/-

Specimen 5B Forelimb Shh-/-Msx1-/-Msx2-/-: embryonic day 11.5; Msx1^tm1Bero/Msx1^tm1Bero, Msx2^tm1Bero/Msx2^tm1Bero, Shh^tm1Amc/Shh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS19: forelimb bud	Present	Regionally restricted	5B FL Shh-/- Msx1-/- Msx2-/-	No significant modification of expression compared to Shh-/- mutant.

Specimen 5B Hindlimb Control: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: hindlimb bud	Present	Regionally restricted	5B HL Control

5B HL Shh-/- ©

Specimen 5B Hindlimb Shh-/-: embryonic day 11.5; Shh^tm1Amc/Shh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS19: hindlimb bud	Present	Regionally restricted	5B HL Shh-/-	Expression comparable to that of controls, but not as polarized.

Specimen 5B Hindlimb Shh-/-Msx1-/-Msx2+/-: embryonic day 11.5; Msx1^tm1Bero/Msx1^tm1Bero, Msx2^tm1Bero/Msx2⁺, Shh^tm1Amc/Shh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS19: hindlimb bud	Present	Regionally restricted	5B HL Shh-/- Msx1-/- Msx2+/-

Specimen 5B Hindlimb Shh-/-Msx1-/-Msx2-/-: embryonic day 11.5; Msx1^tm1Bero/Msx1^tm1Bero, Msx2^tm1Bero/Msx2^tm1Bero, Shh^tm1Amc/Shh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS19: hindlimb bud	Present	Regionally restricted	5B HL Shh-/- Msx1-/- Msx2-/-	No significant modification of expression compared to Shh-/- mutant.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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