Grem1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:150759 Lallemand Y, et al., Msx genes are important apoptosis effectors downstream of the Shh/Gli3 pathway in the limb. Dev Biol. 2009 Jul 15;331(2):189-98
Assay type:	RNA in situ
MGI Accession ID:	MGI:6404393
Gene symbol:	Grem1
Gene name:	gremlin 1, DAN family BMP antagonist

Probe:

Grem1 probe9

Results

Specimen 5A Forelimb Control: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: forelimb bud	Present		5A FL Control

5A FL Shh-/- ©

Specimen 5A Forelimb Shh-/-: embryonic day 11.5; Shh^tm1Amc/Shh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS19: forelimb bud	Ambiguous		5A FL Shh-/-	Expression downregulated.

Specimen 5A Forelimb Shh-/-Msx1-/-Msx2+/-: embryonic day 11.5; Msx1^tm1Bero/Msx1^tm1Bero, Msx2^tm1Bero/Msx2⁺, Shh^tm1Amc/Shh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS19: forelimb bud	Ambiguous		5A FL Shh-/- Msx1-/- Msx2+/-

Specimen 5A Forelimb Shh-/-Msx1-/-Msx2-/-: embryonic day 11.5; Msx1^tm1Bero/Msx1^tm1Bero, Msx2^tm1Bero/Msx2^tm1Bero, Shh^tm1Amc/Shh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS19: forelimb bud	Ambiguous		5A FL Shh-/- Msx1-/- Msx2-/-	Expression not recovered.

Specimen 5A Hindlimb Control: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: hindlimb bud	Present		5A HL Control

5A HL Shh-/- ©

Specimen 5A Hindlimb Shh-/-: embryonic day 11.5; Shh^tm1Amc/Shh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS19: hindlimb bud	Ambiguous		5A HL Shh-/-

Specimen 5A Hindlimb Shh-/-Msx1-/-Msx2+/-: embryonic day 11.5; Msx1^tm1Bero/Msx1^tm1Bero, Msx2^tm1Bero/Msx2⁺, Shh^tm1Amc/Shh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS19: hindlimb bud	Ambiguous		5A HL Shh-/- Msx1-/- Msx2+/-	Expression downregulated.

Specimen 5A Hindlimb Shh-/-Msx1-/-Msx2-/-: embryonic day 11.5; Msx1^tm1Bero/Msx1^tm1Bero, Msx2^tm1Bero/Msx2^tm1Bero, Shh^tm1Amc/Shh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS19: hindlimb bud	Ambiguous		5A HL Shh-/- Msx1-/- Msx2-/-	Expression not recovered.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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