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Gene Expression Data
Assay Details
Assay
Reference: J:228873 Stathopoulou A, et al., Inactivation of Geminin in neural crest cells affects the generation and maintenance of enteric progenitor cells, leading to enteric aganglionosis. Dev Biol. 2016 Jan 15;409(2):392-405
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6400291
Gene symbol: Gmnn
Gene name: geminin
Antibody: anti-gemenin
Detection system: Alexa Fluor 568
Results
Specimen 1A: embryonic day 10.5; Gmnntm1.1Kio/Gmnn+, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - Gmnn; green - Cre reporter.
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 1A
TS17: neural tube Present 1A
TS17: sympathetic nervous system Present Regionally restricted 1A Expression in sympathetic ganglia.
TS17: migrating neural crest Present Regionally restricted 1A Expression in neural crest cells migrating to developing gut.
Specimen 1B: embryonic day 10.5; Gmnntm1.1Kio/Gmnntm1.1Kio, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - Gmnn; green - Cre reporter.
Structure Level Pattern Image Note
TS17: migrating neural crest Absent 1B Expression undetectable or absent in neural crest cells migrating to developing gut.
Specimen 1C: embryonic day 10.5; Gmnntm1.1Kio/Gmnn+, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - Gmnn; green - Cre reporter.
Structure Level Pattern Image Note
TS17: migrating neural crest Present Regionally restricted 1C Expression in neural crest cells migrating to developing gut.
Specimen 1D: embryonic day 10.5; Gmnntm1.1Kio/Gmnntm1.1Kio, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - Gmnn; green - Cre reporter.
Structure Level Pattern Image Note
TS17: migrating neural crest Absent 1D Expression undetectable or absent in neural crest cells migrating to developing gut.
Specimen 1E: embryonic day 10.5; Gmnntm1.1Kio/Gmnn+, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - Gmnn; green - Cre reporter.
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 1E
TS17: neural tube Present 1E
TS17: migrating neural crest Present Regionally restricted 1E Expression in neural crest cells migrating to developing heart.
Specimen 1F: embryonic day 10.5; Gmnntm1.1Kio/Gmnntm1.1Kio, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - Gmnn; green - Cre reporter.
Structure Level Pattern Image Note
TS17: migrating neural crest Absent 1F Expression undetectable or absent in neural crest cells migrating to developing heart
Specimen 1G: embryonic day 10.5; Gmnntm1.1Kio/Gmnn+, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - Gmnn; green - Cre reporter.
Structure Level Pattern Image Note
TS17: migrating neural crest Present Regionally restricted 1G Expression in neural crest cells migrating to developing heart.
Specimen 1H: embryonic day 10.5; Gmnntm1.1Kio/Gmnntm1.1Kio, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - Gmnn; green - Cre reporter.
Structure Level Pattern Image Note
TS17: migrating neural crest Absent 1H Expression undetectable or absent in neural crest cells migrating to developing heart
Specimen not shown: embryonic day 10.5; Gmnntm1.1Kio/Gmnntm1.1Kio, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: dorsal root ganglion Absent Authors report expression undetectable or absent in dorsal root ganglia.
TS17: sympathetic nervous system Absent Authors report expression undetectable or absent in sympathetic ganglia.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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