Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:201153 Hamard PJ, et al., The C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivo. Genes Dev. 2013 Sep 1;27(17):1868-85
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6383910
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:

Results

Specimen 5D p53 +/+: postnatal day 10 (more

)

Structure	Level	Pattern	Image	Note
TS28: bone marrow	Absent		5D p53 +/+ (bottom)	No apoptosis detected in bone marrow cells from all genotypes.

Specimen 5D p53 deltaCTD/+: postnatal day 10; Trp53^tm1.1Manf/Trp53⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: bone marrow	Absent		5D p53 deltaCTD/+ (bottom)	No apoptosis detected in bone marrow cells from all genotypes.

Specimen 5D p53 deltaCTD/deltaCTD: postnatal day 10; Trp53^tm1.1Manf/Trp53^tm1.1Manf (more

)

Structure	Level	Pattern	Image	Note
TS28: bone marrow	Absent		5D p53 deltaCTD/deltaCTD (bottom)	No apoptosis detected in bone marrow cells from all genotypes.

Specimen 5D p53 -/-: postnatal day 10; Trp53^tm1Tyj/Trp53^tm1Tyj (more

)

Structure	Level	Pattern	Image	Note
TS28: bone marrow	Absent		5D p53 -/- (bottom)	No apoptosis detected in bone marrow cells from all genotypes.

7A p53 +/+ ©

Specimen 7A p53 +/+: postnatal day 10 (more

)

Structure	Level	Pattern	Image	Note
TS28: thymus	Absent		7A p53 +/+	No evidence of expression in wild type or heterozygous tissue.

Specimen 7A p53 deltaCTD/+: postnatal day 10; Trp53^tm1.1Manf/Trp53⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: thymus	Absent		7A p53 deltaCTD/+	No evidence of expression in wild type or heterozygous tissue.

Specimen 7A p53 deltaCTD/deltaCTD: postnatal day 10; Trp53^tm1.1Manf/Trp53^tm1.1Manf (more

)

Structure	Level	Pattern	Image	Note
TS28: thymus	Present		7A p53 deltaCTD/deltaCTD	Authors report clear evidence of expressing cells.

Specimen 9D p53 +/+: postnatal day 10 (more

)

Structure	Level	Pattern	Image	Note
TS28: spleen	Absent		9D p53 +/+ (bottom)	No evidence of expression in wild type or heterozygous tissue.

Specimen 9D p53 deltaCTD/+: postnatal day 10; Trp53^tm1.1Manf/Trp53⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: spleen	Absent		9D p53 deltaCTD/+ (bottom)	No evidence of expression in wild type or heterozygous tissue.

Specimen 9D p53 deltaCTD/deltaCTD: postnatal day 10; Trp53^tm1.1Manf/Trp53^tm1.1Manf (more

)

Structure	Level	Pattern	Image	Note
TS28: spleen	Absent		9D p53 deltaCTD/deltaCTD (bottom)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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