About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:273053 Shih HP, et al., A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells. Cell Rep. 2015 Oct 13;13(2):326-36
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6361258
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: Anti-Sox2 (Y-17; sc-17320)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: Two antibodies were described, but the one used in this assay was not specified; either MGI:5430034 or MGI:5762877 could have been used.
Results
Specimen 2A: embryonic day 8.75 (more )
Note: Triple labeled: green - Sox2; red - Sox9 (assay MGI:6361259); white - Pdx1 (assay MGI:6361260).
Structure Level Pattern Image Note
TS13: foregut diverticulum Present Regionally restricted 2A'' , 2A The Sox2-positive domain, from which the stomach develops, formed a boundary with both the Pdx1+ and Sox9+ domains. Very few cells co-expressing Sox2, Pdx1, and Sox9 were observed at this boundary.
Specimen 2C: embryonic day 10.5 (more )
Note: Triple labeled: green - Sox2; red - Cdx2 (assay MGI:6361262); blue - Pdx1 (assay MGI:6361260).
Structure Level Pattern Image Note
TS17: stomach Present 2C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory