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Gene Expression Data
Assay Details
Assay
Reference: J:273053 Shih HP, et al., A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells. Cell Rep. 2015 Oct 13;13(2):326-36
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6361260
Gene symbol: Pdx1
Gene name: pancreatic and duodenal homeobox 1
Antibody: Anti-Pdx1
Assay notes: Two antibodies were described, but the one used in this assay was not specified; either MGI:6361200 or MGI:6361201 could have been used.
Results
Specimen 2A: embryonic day 8.75 (more )
Note: Triple labeled: white - Pdx1; green - Sox2 (assay MGI:6361258); red - Sox9 (assay MGI:6361259).
Structure Level Pattern Image Note
TS13: foregut-midgut junction Present Regionally restricted 2A , 2A' Expression was restricted to the pre-pancreatic domain. The Sox2-positive domain, from which the stomach develops, formed a boundary with both the Pdx1+ and Sox9+ domains. Very few cells co-expressing Sox2, Pdx1, and Sox9 were observed at this boundary.
Specimen 2B: embryonic day 8.75 (more )
Note: Triple labeled: white - Pdx1; green - Cdx2 (assay MGI:6361261); red - Sox9 (assay MGI:6361259).
Structure Level Pattern Image Note
TS13: foregut-midgut junction Present Regionally restricted 2B' , 2B Expression was restricted to the pre-pancreatic domain.
Specimen 2C: embryonic day 10.5 (more )
Note: Triple labeled: blue - Pdx1; green - Sox2 (assay MGI:6361258); red - Cdx2 (assay MGI:6361262).
Structure Level Pattern Image Note
TS17: pancreas primordium Present 2C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory