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Gene Expression Data
Assay Details
Assay
Reference: J:208424 Yoshida M, et al., Regulation of mesodermal precursor production by low-level expression of B1 Sox genes in the caudal lateral epiblast. Mech Dev. 2014 May;132:59-68
Assay type: RNA in situ
MGI Accession ID: MGI:5811535
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Results
Specimen 1Aa: embryonic day 8.0 (more )
Note: 3-4 somite stage
Structure Level Pattern Image Note
TS12: non-neural ectoderm Present Regionally restricted 1Aa Expression in caudal lateral epiblast (CLE) region adjacent to primitive streak, at lower levels compared with neural plate regions.
TS12: neural plate Strong 1Aa

Specimen 1Ab: embryonic day 8.0 (more )
Note: 5 somite stage
Structure Level Pattern Image Note
TS12: non-neural ectoderm Present Regionally restricted 1Ab Expression starts at node level and proceeds toward posterior end.

Specimen 1Ac: embryonic day 8.0 (more )
Note: 7 somite stage
Structure Level Pattern Image Note
TS12: non-neural ectoderm Present Regionally restricted 1Ac Expression starts at node level and proceeds toward posterior end.

Specimen 1Ag: embryonic day 8.0; Sox2tm1.1Knd/Sox2tm1.1Knd (more )
Note: 3-4 somite stage
Structure Level Pattern Image Note
TS12: non-neural ectoderm Present Regionally restricted 1Ag Expression pattern was little affected compared with wild type embryos.

Specimen 1Ah: embryonic day 8.0; Sox2tm1.1Knd/Sox2tm1.1Knd (more )
Note: 5 somite stage
Structure Level Pattern Image Note
TS12: non-neural ectoderm Present Regionally restricted 1Ah Expression lost posterior to the node.

Specimen 1Ai: embryonic day 8.0; Sox2tm1.1Knd/Sox2tm1.1Knd (more )
Note: 7 somite stage
Structure Level Pattern Image Note
TS12: non-neural ectoderm Present Regionally restricted 1Ai Expression absent in area extending to level anterior to the node.

Specimen 1Ba: embryonic day 8.0; Sox3tm1Rlb/Sox3tm1Rlb (more )
Note: 5 somite stage
Structure Level Pattern Image Note
TS12: non-neural ectoderm Present Regionally restricted 1Ba Expression indistinguishable from that of wild-type embryos.

Specimen 1Bb: embryonic day 8.0; Sox2tm1.1Knd/Sox2tm1.1Knd, Sox3tm1Rlb/Sox3tm1Rlb (more )
Note: 5 somite stage
Structure Level Pattern Image Note
TS12: non-neural ectoderm Present Regionally restricted 1Bb Expression indistinguishable from that of Sox2deltaN1/deltaN1 embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory