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Gene Expression Data
Assay Details
Assay
Reference: J:79480 Natarajan D, et al., Requirement of signalling by receptor tyrosine kinase RET for the directed migration of enteric nervous system progenitor cells during mammalian embryogenesis. Development. 2002 Nov;129(22):5151-60
Assay type: RNA in situ
MGI Accession ID: MGI:5690128
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Probe: Sox10 cDNA6
Probe preparation: Antisense RNA
Results
Specimen 4A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS16: cranial ganglion Present 4A
TS16: dorsal root ganglion Present 4A
TS16: foregut mesenchyme Present 4A
TS16: migrating neural crest Present Regionally restricted 4A Expression was detected in the postbranchial region.

Specimen 4B: embryonic day 9.5; Rettm1Cos/Rettm1Cos (more )
Structure Level Pattern Image Note
TS16: cranial ganglion Present 4B
TS16: dorsal root ganglion Present 4B
TS16: migrating neural crest Present Regionally restricted 4B Expression was detected in the postbranchial region as in wild type.
TS16: foregut mesenchyme Absent 4B

Specimen 4C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: migrating neural crest Present Regionally restricted 4C Migrating enteric nervous system progenitors had reached the midgut loop (halfway between the caudal end of the pancreas and the caecum).

Specimen 4D: embryonic day 10.5; Rettm2(RET)Vpa/Rettm2(RET)Vpa (more )
Structure Level Pattern Image Note
TS17: migrating neural crest Present Regionally restricted 4D The frong of migrating enteric neural crest cells was located more anteriorly compared to wild type, just beyond the pancreatic anlage. The total number of stained cells was reduced in the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory