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Gene Expression Data
Assay Details
Assay
Reference: J:148533 Saito K, et al., Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis. Proc Natl Acad Sci U S A. 2009 May 19;106(20):8350-5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5661041
Gene symbol: Fdft1
Gene name: farnesyl diphosphate farnesyl transferase 1
Antibody: SQS antibody
Detection system: Secondary antibody coupled to Cy3
Results
Specimen S1C E11.5 telencephalon con: embryonic day 11.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS19: telencephalon Present S1C E11.5 telencephalon con
Specimen S1C E11.5 diencephalon con: embryonic day 11.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS19: diencephalon Present S1C E11.5 diencephalon con
Specimen S1C E12.5 telencephalon con: embryonic day 12.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS20: telencephalon Present S1C E12.5 telencephalon con
Specimen S1C E12.5 diencephalon con: embryonic day 12.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS20: diencephalon Present S1C E12.5 diencephalon con
Specimen S1C E13.5 telencephalon con: embryonic day 13.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS21: telencephalon Present S1C E13.5 telencephalon con
Specimen S1C E13.5 telencephalon cKO: embryonic day 13.5; Fdft1tm1Kan/Fdft1tm1Kan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: telencephalon Weak Regionally restricted S1C E13.5 telencephalon cKO Authors report a marked reduction in expression in the ventricular zone and, to a lesser extent, in the neuronal layers.
TS21: telencephalon ventricular layer Weak S1C E13.5 telencephalon cKO Expression most rescued in ventricular zone progenitors.
Specimen S1C E13.5 diencephalon con: embryonic day 13.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS21: diencephalon Present S1C E13.5 diencephalon con
Specimen S1C E13.5 diencephalon cKO: embryonic day 13.5; Fdft1tm1Kan/Fdft1tm1Kan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: diencephalon Weak Regionally restricted S1C E13.5 diencephalon cKO Authors report a marked reduction in expression in the ventricular zone and, to a lesser extent, in the neuronal layers.
TS21: diencephalon ventricular layer Weak S1C E13.5 diencephalon cKO Expression most rescued in ventricular zone progenitors.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory