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Gene Expression Data
Assay Details
Assay
Reference: J:148533 Saito K, et al., Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis. Proc Natl Acad Sci U S A. 2009 May 19;106(20):8350-5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5661036
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-activated caspase-3
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 2A telencephalon E11.5 control: embryonic day 11.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS19: telencephalon Ambiguous 2A telencephalon E11.5 control merge , 2A telencephalon E11.5 caspase 3 control Very few apoptotic cells were detected in control brain tissue at any stage.
Specimen 2A telencephalon E11.5 SQS-cKO: embryonic day 11.5; Fdft1tm1Kan/Fdft1tm1Kan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: telencephalon Ambiguous 2A telencephalon E11.5 SQS-cKO merge , 2A telencephalon E11.5 caspase3 SQS-cKO
Specimen 2A telencephalon E12.5 control: embryonic day 12.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS20: telencephalon Ambiguous 2A telencephalon E12.5 control merge , 2A telencephalon E12.5 caspase 3 control Very few apoptotic cells were detected in control brain tissue at any stage.
Specimen 2A telencephalon E12.5 SQS-cKO: embryonic day 12.5; Fdft1tm1Kan/Fdft1tm1Kan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: telencephalon Ambiguous 2A telencephalon E12.5 caspase3 SQS-cKO , 2A telencephalon E12.5 SQS-cKO merge
Specimen 2A telencephalon E13.5 control: embryonic day 13.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS21: telencephalon Ambiguous 2A telencephalon E13.5 control merge , 2A telencephalon E13.5 caspase 3 control Very few apoptotic cells were detected in control brain tissue at any stage.
Specimen 2A telencephalon E13.5 SQS-cKO: embryonic day 13.5; Fdft1tm1Kan/Fdft1tm1Kan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: telencephalon Present Regionally restricted 2A telencephalon E13.5 caspase3 SQS-cKO , 2A telencephalon E13.5 SQS-cKO merge Authors report apoptotic cells were frequently observed.
Specimen 2A telencephalon E15.5 control: embryonic day 15.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS23: telencephalon Ambiguous 2A telencephalon E15.5 caspase 3 control , 2A telencephalon E15.5 control merge Very few apoptotic cells were detected in control brain tissue at any stage.
Specimen 2A telencephalon E15.5 SQS-cKO: embryonic day 15.5; Fdft1tm1Kan/Fdft1tm1Kan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: telencephalon Present Regionally restricted 2A telencephalon E15.5 SQS-cKO merge , 2A telencephalon E15.5 caspase3 SQS-cKO Authors report apoptotic cells were observed even more frequently.
Specimen 2A diencephalon E11.5 control: embryonic day 11.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS19: diencephalon Ambiguous 2A diencephalon E11.5 control merge , 2A diencephalon E11.5 caspase 3 control Very few apoptotic cells were detected in control brain tissue at any stage.
Specimen 2A diencephalon E11.5 SQS-cKO: embryonic day 11.5; Fdft1tm1Kan/Fdft1tm1Kan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: diencephalon Ambiguous 2A diencephalon E11.5 SQS-cKO merge , 2A diencephalon E11.5 caspase3 SQS-cKO
Specimen 2A diencephalon E12.5 control: embryonic day 12.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS20: diencephalon Ambiguous 2A diencephalon E12.5 control merge , 2A diencephalon E12.5 caspase 3 control Very few apoptotic cells were detected in control brain tissue at any stage.
Specimen 2A diencephalon E12.5 SQS-cKO: embryonic day 12.5; Fdft1tm1Kan/Fdft1tm1Kan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted 2A diencephalon E12.5 caspase3 SQS-cKO , 2A diencephalon E12.5 SQS-cKO merge Authors report apoptotic cells were frequently observed.
Specimen 2A diencephalon E13.5 control: embryonic day 13.5; Fdft1tm1Kan/Fdft1tm1Kan (more )
Structure Level Pattern Image Note
TS21: diencephalon Ambiguous 2A diencephalon E13.5 caspase 3 control , 2A diencephalon E13.5 control merge Very few apoptotic cells were detected in control brain tissue at any stage.
Specimen 2A diencephalon E13.5 SQS-cKO: embryonic day 13.5; Fdft1tm1Kan/Fdft1tm1Kan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 2A diencephalon E13.5 caspase3 SQS-cKO , 2A diencephalon E13.5 SQS-cKO merge Apoptotic cells were massively observed.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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