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Gene Expression Data
Assay Details
Assay
Reference: J:58233 Eisenstat DD, et al., DLX-1, DLX-2, and DLX-5 expression define distinct stages of basal forebrain differentiation. J Comp Neurol. 1999 Nov 15;414(2):217-37
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5523861
Gene symbol: Dlx1
Gene name: distal-less homeobox 1
Antibody: anti-DLX-1/N114
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2E: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: telencephalon Present 2E Expression is in the subcortical telencephalon, itincludes the large ganglionic eminence, the medial ganglionic eminence, the preoptic area, the anterior entopeduncular area, and parts of the septal and amygdalar primordia.
TS18: diencephalon Present Regionally restricted 2E Expression is in the rostral diencephalon and hypothalamus just anterior of the zona limitans intrathalamica, extending through the ventral thalamus, the supraoptoparaventricular area, the hypothalamic cell cord, and ending in the suprachiasmatic area.
TS18: diencephalon lateral wall ventricular layer Present Regionally restricted 2E
TS18: telencephalon ventricular layer Present Regionally restricted 2E
TS18: diencephalon lateral wall mantle layer Present Regionally restricted 2E
TS18: telencephalon mantle layer Present Regionally restricted 2E

Specimen 2K: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: telencephalon ventricular layer Present 2K
TS18: telencephalon mantle layer Present 2K

Specimen 2Q: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: telencephalon ventricular layer Present 2Q
TS18: telencephalon mantle layer Present 2Q

Specimen 3H: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: diencephalon Present Regionally restricted 3H Expression is in the rostral diencephalon and hypothalamus just anterior of the zona limitans intrathalamica, extending through the ventral thalamus, the supraoptoparaventricular area, the hypothalamic cell cord, and ending in the suprachiasmatic area.

Specimen 3K: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: diencephalon Present Regionally restricted 3K Expression is in the supraoptoparaventricular area and ventral thalamus with a caudal limit at the zona limitans intrathalamica.

Specimen 3S: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: diencephalon Present Regionally restricted 3S Expression is in the hypothalamus.

Specimen 4E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ganglionic eminence Present 4E

Specimen 4K: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted 4K Expression is in nascent nuclei within prosomere 3 and 4 and in periventricular cell populations that may contribute to the zona incerta and to the paraventricular nucleus.

Specimen 4O: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hypothalamus Present Regionally restricted 4O

Specimen 4R: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hypothalamus Present Regionally restricted 4R

Specimen 5A: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx1; blue/purple - Dlx2 (assay MGI:5523240).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5A Expression is in the medial ganglionic eminence (shown is the ventricular zone).

Specimen 5D: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx1; blue/purple - Dlx2 (assay MGI:5523240).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5D Expression is in the medial ganglionic eminence (shown is the subventricular zone).

Specimen 5E: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx1; blue/purple - Dlx2 (assay MGI:5523240).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5E Expression is in the medial ganglionic eminence.

Specimen 5K: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx1; blue/purple - Dlx1 (assay MGI:5523863).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5K Expression is in the medial ganglionic eminence (shown is the ventricular zone).

Specimen 5L: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx1; blue/purple - Dlx1 (assay MGI:5523863).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5L Expression is in the medial ganglionic eminence (shown is the subventricular zone).

Specimen 5R: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx1; blue/purple - Dlx5 (assay MGI:5523864).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5R Expression is in the medial ganglionic eminence.

Specimen 5S: embryonic day 11.0 (more )
Note: Double labeled: brown/red - Dlx1; blue/purple - Dlx5 (assay MGI:5523864).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5S Expression is in the medial ganglionic eminence (shown is the ventricular zone).

Specimen 9H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 9H Expression is in the ganglionic eminence primarily subpially with a few cells in the ventricular zone.

Specimen 9J: embryonic day 10.5; Dlx2tm1Jlr/Dlx2tm1Jlr (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 9J There are fewer expressing cells in the ventricular zone of the lateral ganglionic eminence in this mutant.

Specimen 10B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: neural retinal epithelium Present 10B
TS20: cornea Absent 10B
TS20: lens vesicle Absent 10B
TS20: pigmented retinal epithelium Absent 10B


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory