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Gene Expression Data
Assay Details
Assay
Reference: J:85738 MacLean HE, et al., Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development. Dev Biol. 2003 Oct 1;262(1):51-63
Assay type: RNA in situ
MGI Accession ID: MGI:5505428
Gene symbol: Col10a1
Gene name: collagen, type X, alpha 1
Probe: Col10a1 cDNA2
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 1C E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tibia cartilage condensation Present Regionally restricted 1C E14.5 Expression was detected by all hypertrophic chondrocytes, at high levels in early hypertrophic cells and lower levels in late hypertrophic chondrocytes.

Specimen 1C E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: tibia Present Regionally restricted 1C E15.5 Expression was detected by all hypertrophic chondrocytes, at high levels in early hypertrophic cells and lower levels in late hypertrophic chondrocytes.

Specimen 1C E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: tibia Present Regionally restricted 1C E16.5 Expression was detected by all hypertrophic chondrocytes, at high levels in early hypertrophic cells and lower levels in late hypertrophic chondrocytes.

Specimen 1C E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: tibia Present Regionally restricted 1C E17.5 Expression was detected by all hypertrophic chondrocytes, at high levels in early hypertrophic cells and lower levels in late hypertrophic chondrocytes.

Specimen 1C E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: tibia Present Regionally restricted 1C E18.5 Expression was detected by all hypertrophic chondrocytes, at high levels in early hypertrophic cells and lower levels in late hypertrophic chondrocytes.

Specimen 1C 24d: postnatal day 24 (more )
Structure Level Pattern Image Note
TS28: tibia Present Regionally restricted 1C 24d Expression was detected by all hypertrophic chondrocytes, at high levels in early hypertrophic cells and lower levels in late hypertrophic chondrocytes.

Specimen 3A +/+: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tibia cartilage condensation Present Regionally restricted 3A +/+ collagen X Expression was detected in hypertrophic chondrocytes.

Specimen 3A -/-: embryonic day 14.5; Maftm1Glm/Maftm1Glm (more )
Structure Level Pattern Image Note
TS22: tibia cartilage condensation Present Regionally restricted 3A -/- collagen X Normal expression was detected in hypertrophic chondrocytes.

Specimen 3B +/+: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: tibia Present Regionally restricted 3B +/+ collagen X Expression was detected in hypertrophic chondrocytes.

Specimen 3B -/-: embryonic day 15.5; Maftm1Glm/Maftm1Glm (more )
Structure Level Pattern Image Note
TS23: tibia Present Regionally restricted 3B -/- collagen X Expression intensity in hypertrophic chondrocytes was normal, but the domain was decreased in the mutant.

Specimen 3C +/+: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: tibia Present Regionally restricted 3C +/+ collagen X Expression was detected in hypertrophic chondrocytes.

Specimen 3C -/-: embryonic day 16.5; Maftm1Glm/Maftm1Glm (more )
Structure Level Pattern Image Note
TS24: tibia Present Regionally restricted 3C -/- collagen X The expression domain in hypertrophic chondrocytes expanded in the mutant at E16.5.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory