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Gene Expression Data
Assay Details
Assay
Reference: J:95017 Parlato R, et al., An integrated regulatory network controlling survival and migration in thyroid organogenesis. Dev Biol. 2004 Dec 15;276(2):464-75
Assay type: RNA in situ
MGI Accession ID: MGI:5495932
Gene symbol: Hhex
Gene name: hematopoietically expressed homeobox
Probe: Hhex probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2I: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: thyroid primordium Present 2I
Specimen 2J: embryonic day 9.0; Nkx2-1tm1Shk/Nkx2-1tm1Shk (more )
Structure Level Pattern Image Note
TS14: thyroid primordium Present 2J Expression is comparable to those of the wild-type bud.
Specimen 2K: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present 2K
Specimen 2L: embryonic day 10.0; Nkx2-1tm1Shk/Nkx2-1tm1Shk (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Trace 2L Strong reduction in expression level, compared with those of the wild type. Expression is hardly detectable.
Specimen 3I: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: thyroid primordium Present 3I
Specimen 3J: embryonic day 9.0; Pax8tm1Pgr/Pax8tm1Pgr (more )
Structure Level Pattern Image Note
TS14: thyroid primordium Present 3J Expression is unchanged compared to the wild type.
Specimen 3K: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present 3K
Specimen 3L: embryonic day 10.0; Pax8tm1Pgr/Pax8tm1Pgr (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Trace 3L Almost undetectable.
Specimen 4A: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present 4A
Specimen 4B: embryonic day 10.0; Foxe1tm1Rdl/Foxe1tm1Rdl (more )
Structure Level Pattern Image Note
TS16: thyroid primordium Present 4B Expression is comparable to those of the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory