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Gene Expression Data
Assay Details
Assay
Reference: J:133947 Summerhurst K, et al., 3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19). Gene Expr Patterns. 2008 May;8(5):331-48
Assay type: RNA in situ
MGI Accession ID: MGI:5448681
Gene symbol: Fzd1
Gene name: frizzled class receptor 1
Probe: Fzd1 cDNA2
Probe preparation: Antisense RNA
Assay notes: These data are obtained from optical projection tomography (OPT).
Results
Specimen 1I: embryonic day 11.5 (more )
Note: Left side is OPT reconstructed data, right side is the corresponding whole-mount in situ hybridized embryo.
Structure Level Pattern Image Note
TS19: embryo Present 1I
Specimen 2A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 2A Expression is in a lateral stripe in the hindbrain just posterior to the midbrain hindbrain boundary.
TS19: lens vesicle Present Regionally restricted 2A In the anterior walls.
TS19: maxillary process Present Patchy 2A Complex anterior pattern.
TS19: mandibular process Present Patchy 2A Complex posterior pattern.
TS19: 2nd branchial arch Present Patchy 2A
TS19: forelimb bud mesenchyme Present Patchy 2A Especially anterior and dorsal at the base of the limb.
Specimen 2B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: fronto-nasal process Present Regionally restricted 2B Around the nasal pits.
TS19: body wall Present Regionally restricted 2B Expression is in a lateral body wall domain extending between the fore- and hindlimbs.
Specimen 2C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: embryo Present 2C
Specimen 2D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: embryo Present 2D
Specimen 2E, E': embryonic day 11.5 (more )
Note: virtual section
Structure Level Pattern Image Note
TS19: embryo Present 2E' , 2E
Specimen 2F, F': embryonic day 11.5 (more )
Note: virtual section
Structure Level Pattern Image Note
TS19: fronto-nasal process Present Regionally restricted 2F , 2F' Around the nasal pits.
TS19: body wall Present Regionally restricted 2F' , 2F Expression is in the body wall around the heart.
Specimen 2G, G': embryonic day 11.5 (more )
Note: virtual section
Structure Level Pattern Image Note
TS19: myotome Present 2G' , 2G
Specimen 2H, H': embryonic day 11.5 (more )
Note: virtual section
Structure Level Pattern Image Note
TS19: midbrain mantle layer Present Regionally restricted 2H' , 2H Dorsolateral expression.
TS19: hindbrain Present Regionally restricted 2H' , 2H Expression is in a lateral stripe in the hindbrain just posterior to the midbrain hindbrain boundary.
Specimen 2I, I': embryonic day 11.5 (more )
Note: virtual section
Structure Level Pattern Image Note
TS19: telencephalon Present 2I , 2I' Lateral expression.
Specimen 2J, J': embryonic day 11.5 (more )
Note: virtual section
Structure Level Pattern Image Note
TS19: embryo Present 2J' , 2J
Specimen 2K, K': embryonic day 11.5 (more )
Note: virtual section
Structure Level Pattern Image Note
TS19: embryo Present 2K , 2K'
Specimen Table 1: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: 1st branchial arch Present
TS19: 2nd branchial arch Present
TS19: apical ectodermal ridge Present
TS19: body wall Present
TS19: eye Present
TS19: forelimb bud mesenchyme Present
TS19: fronto-nasal process Present
TS19: hindbrain Present
TS19: midbrain Present
TS19: surface ectoderm Present
TS19: telencephalon Present
Specimen 5 first: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Patchy 5_Fzd1 first
TS19: apical ectodermal ridge Present 5_Fzd1 first
TS19: forelimb bud ectoderm Present 5_Fzd1 first Expression is in the ectoderm adjacent to the AER.
Specimen 5 second: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Patchy 5_Fzd1 second
TS19: apical ectodermal ridge Present 5_Fzd1 second
Specimen 5 third: embryonic day 11.5 (more )
Note: virtual section
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Patchy 5_Fzd1 third
TS19: apical ectodermal ridge Present 5_Fzd1 third
Specimen 5 fourth: embryonic day 11.5 (more )
Note: virtual section
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Patchy 5_Fzd1 fourth
TS19: apical ectodermal ridge Present 5_Fzd1 fourth
Specimen 5 fifth: embryonic day 11.5 (more )
Note: virtual section
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Patchy 5_Fzd1 fifth
TS19: apical ectodermal ridge Present 5_Fzd1 fifth
Specimen 5 sixth: embryonic day 11.5 (more )
Note: virtual section
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Patchy 5_Fzd1 sixth
TS19: apical ectodermal ridge Present 5_Fzd1 sixth
Specimen 5 seventh: embryonic day 11.5 (more )
Note: virtual section
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Patchy 5_Fzd1 seventh
TS19: apical ectodermal ridge Present 5_Fzd1 seventh
Specimen Table 2: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present
TS19: forelimb bud ectoderm Present
TS19: forelimb bud mesenchyme Present
Specimen Table S1: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: midbrain mantle layer Present Regionally restricted Expression is dorsal.
TS19: telencephalon Present Regionally restricted Mostly lateral.
TS19: hindbrain Present Regionally restricted Expression is in a lateral stripe just posterior to midbrain-hindbrain boundary. Posterior expression is in the ventricular zone with a localised intense patch just dorsal to the floor plate at level anterior to otic vesicle.
TS19: head Present Regionally restricted Complex patches in the facial region and branchial arches including around nasal pits.
TS19: mandibular process Present Regionally restricted Anterior expression.
TS19: maxillary process Present Regionally restricted Anterior expression.
TS19: 2nd branchial arch Present
TS19: apical ectodermal ridge Present
TS19: cornea epithelium Present
TS19: myotome Present
TS19: forelimb bud mesenchyme Present Patchy Particularly high at anterior side. Also patches in mesenchyme at dorsal aspect of base of limbs, particularly strong and extensive toward anterior aspect.
TS19: eye Present Regionally restricted
TS19: lens vesicle Present Regionally restricted Expression is in the anterior wall.
TS19: optic stalk Present Regionally restricted Expression in in a fine line in the ventral part.
TS19: body wall Present Regionally restricted Around the heart.
TS19: trunk Present Regionally restricted Expression is around hypato-cardiac vein, in the myotome and extending into body wall and limb and as a lateral line between limbs.
TS19: surface ectoderm Present Regionally restricted Expresion is in the midline dorsal ectoderm.
Specimen Not shown TS19: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: thymus/parathyroid primordium Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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