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Gene Expression Data
Assay Details
Assay
Reference: J:166449 Nishino J, et al., Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system. J Neurosci. 2010 Nov 10;30(45):15228-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5301087
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Antibody: anti-Human/Rat SOX10
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 5E left: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: sympathetic nervous system Present Regionally restricted 5E left Expressed in neural crest stem/progenitor cells.

Specimen 5E right: embryonic day 10.5; Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Structure Level Pattern Image Note
TS17: sympathetic nervous system Present Regionally restricted 5E right Expressed in neural crest stem/progenitor cells. Normal expression relative to controls.

Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present Regionally restricted Expressed in neural crest stem/progenitor cells.

Specimen not shown: embryonic day 10.5; Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present Regionally restricted Expressed in neural crest stem/progenitor cells. Normal expression relative to controls.

Specimen S7A middle left: embryonic day 13.5 (more )
Note: Double labeled: red - Sox10; green - Casp3 (assay MGI:5301447).
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present S7A middle left , S7A Merged left

Specimen S7A middle right: embryonic day 13.5; Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Note: Double labeled: red - Sox10; green - Casp3 (assay MGI:5301447).
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present S7A middle right , S7A Merged right

Specimen S7C middle left: embryonic day 13.5 (more )
Note: Double labeled: red - Sox10; green - Casp3 (assay MGI:5301447).
Structure Level Pattern Image Note
TS21: gut Present S7C Merged left , S7C middle left

Specimen S7C middle right: embryonic day 13.5; Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Note: Double labeled: red - Sox10; green - Casp3 (assay MGI:5301447).
Structure Level Pattern Image Note
TS21: gut Present S7C middle right , S7C Merged right


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory