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Gene Expression Data
Assay Details
Assay
Reference: J:166449 Nishino J, et al., Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system. J Neurosci. 2010 Nov 10;30(45):15228-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5301447
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-activated Caspase-3
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: The antibody used recognizes the activated form of the protein.
Results
Specimen S7A top left: embryonic day 13.5 (more )
Note: Double labeled: green - Casp3; red - Sox10 (assay MGI:5301087).
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present Single cells S7A Merged left , S7A top left
Specimen S7A top right: embryonic day 13.5; Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Note: Double labeled: green - Casp3; red - Sox10 (assay MGI:5301087).
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present Single cells S7A Merged right , S7A top right Normal expression relative to controls.
Specimen S7C top left: embryonic day 13.5 (more )
Note: Double labeled: green - Casp3; red - Sox10 (assay MGI:5301087).
Structure Level Pattern Image Note
TS21: enteric nervous system Present Single cells S7C top left , S7C Merged left Positive cells were rare.
Specimen S7C top right: embryonic day 13.5; Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Note: Double labeled: green - Casp3; red - Sox10 (assay MGI:5301087).
Structure Level Pattern Image Note
TS21: enteric nervous system Present Single cells S7C Merged right , S7C top right Normal expression relative to controls. Positive cells were rare.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory