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Gene Expression Data
Assay Details
Assay
Reference: J:132977 McGlinn E, et al., Expression of the NET family member Zfp503 is regulated by hedgehog and BMP signaling in the limb. Dev Dyn. 2008 Apr;237(4):1172-82
Assay type: RNA in situ
MGI Accession ID: MGI:3785618
Gene symbol: Zfp503
Gene name: zinc finger protein 503
Probe: NIA clone H3140A03
Probe preparation: Antisense RNA
Results
Specimen 1A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present Regionally restricted 1A Expression is in the lateral edges of the neural plate.
TS13: future brain neural fold Present 1A
TS13: future hindbrain Present 1A
TS13: trunk somite Present 1A
TS13: trunk unsegmented mesenchyme Present 1A

Specimen 1B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component ectoderm Present 1B
TS15: 1st branchial arch maxillary component ectoderm Present 1B
TS15: 2nd branchial arch Present 1B
TS15: nose Present Regionally restricted 1B Expression is in the olfactory epithelium surrounding the nasal pits.
TS15: forelimb bud ectoderm Present 1B Expression is in the apical ectodermal ridge.

Specimen 1C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: rhombomere 1 Present 1C Expression extends to the rhombomere 1/2 boundary.
TS15: rhombomere 2 Absent 1C

Specimen 1D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: olfactory epithelium Present Regionally restricted 1D Expression is in the olfactory epithelium surrounding the nasal pits.
TS17: 1st branchial arch mandibular component ectoderm Present 1D
TS17: 1st branchial arch maxillary component ectoderm Present 1D
TS17: 2nd branchial arch Present 1D
TS17: forelimb bud apical ectodermal ridge Present 1D
TS17: hindlimb bud apical ectodermal ridge Present 1D

Specimen 1E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: olfactory epithelium Present Regionally restricted 1E Expression is in the olfactory epithelium surrounding the nasal pits.
TS17: 1st branchial arch mandibular component ectoderm Present 1E
TS17: 1st branchial arch maxillary component ectoderm Present 1E
TS17: 2nd branchial arch Present 1E

Specimen 1F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: maxilla primordium Present Diffuse 1F
TS19: 2nd branchial arch Present Diffuse 1F Expression is in a distal domain.
TS19: mandible primordium Present Diffuse 1F Expression is in a distal domain.

Specimen 1G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindlimb bud apical ectodermal ridge Present 1G
TS17: hindlimb bud mesenchyme Present Regionally restricted 1G

Specimen 1H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present 1H
TS17: forelimb bud mesenchyme Present Regionally restricted 1H Expression is in the posterior mesenchyme along the entire proximal-distal extent.

Specimen 1I: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate mesenchyme Present Regionally restricted 1I The expression domain is proximally located at the level of the future tarsal/metatarsal elements.

Specimen 1J: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate mesenchyme Present Regionally restricted 1J The expression domain is proximally located at the level of the future tarsal/metatarsal elements and in an anterior domain.

Specimen 3A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb Present Regionally restricted 3A Expression is in an anterior and posterior domain.

Specimen 3B: embryonic day 12.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS20: forelimb Weak Regionally restricted 3B Expression is reduced in the anterior domain and no consistent change was observed in the posterior domain.

Specimen 3C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindlimb Present Regionally restricted 3C Expression is in an anterior and posterior domain.

Specimen 3D: embryonic day 12.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS20: hindlimb Weak Regionally restricted 3D Expression is reduced in the anterior domain and no consistent change was observed in the posterior domain.

Specimen 3E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb Present Regionally restricted 3E Expression is in an anterior and posterior domain.

Specimen 3F: embryonic day 13.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS21: forelimb Weak 3F Expression is reduced in the anterior domain and no consistent change was observed in the posterior domain.

Specimen 3G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hindlimb Present 3G Expression is in an anterior and posterior domain.

Specimen 3H: embryonic day 13.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS21: hindlimb Weak 3H Expression is reduced in the anterior domain and no consistent change was observed in the posterior domain.

Specimen 3I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present 3I

Specimen 3K: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Present 3K

Specimen 3M: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present 3M

Specimen 3O: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindlimb bud mesenchyme Present 3O

Specimen 3Q: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindlimb bud mesenchyme Present Regionally restricted 3Q Expression is present in a posterior domain.
TS19: footplate mesenchyme Present 3Q

Specimen 3R: embryonic day 11.5; Ptch1tm1Bjw/Ptch1tm1Bjw, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: footplate Absent 3R
TS19: hindlimb bud mesenchyme Present Regionally restricted 3R Expression is present in a posterior domain.

Specimen 3S: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: foot mesenchyme Present 3S
TS20: hindlimb mesenchyme Present Regionally restricted 3S Expression is present in a posterior domain.

Specimen 3T: embryonic day 12.5; Ptch1tm1Bjw/Ptch1tm1Bjw, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: foot Absent 3T
TS20: hindlimb mesenchyme Present Regionally restricted 3T Expression is present in a posterior domain.

Specimen Not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: limb Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory