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Gene Expression Data
Assay Details
Assay
Reference: J:83431 Morgan EA, et al., Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia. Development. 2003 Jul;130(14):3095-109
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:2681891
Gene symbol: Hoxa13
Gene name: homeobox A13
Reporter: GFP
Direct Detection
Results
Specimen 1A: embryonic day 12.5; Hoxa13tm1.1Mrc/Hoxa13+ (more )
Structure Level Pattern Image Note
TS20: genital tubercle Present Regionally restricted 1A Expression was detected in the genital tubercle mesenchyme and the urethral plate epithelium.
Specimen 1B: embryonic day 12.5; Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc (more )
Structure Level Pattern Image Note
TS20: genital tubercle Present Regionally restricted 1B Expression was detected in the genital tubercle mesenchyme and the urethral plate epithelium and was not different from the heterozygous embryo.
Specimen 1E: embryonic day 15.5; Hoxa13tm1.1Mrc/Hoxa13+ (more )
Structure Level Pattern Image Note
TS23: male reproductive system Present 1E
TS23: urethra of male Present 1E
Specimen 1F: embryonic day 15.5; Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc (more )
Structure Level Pattern Image Note
TS23: male reproductive system Present 1F No difference in expression was noted between heterozygous and homozygous embryos.
TS23: urethra of male Present 1F No difference in expression was noted between heterozygous and homozygous embryos.
Specimen 2A: embryonic day 11.5; Hoxa13tm1.1Mrc/Hoxa13+ (more )
Structure Level Pattern Image Note
TS19: genital tubercle Present 2A
Specimen 2B: embryonic day 11.5; Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc (more )
Structure Level Pattern Image Note
TS19: genital tubercle Present 2B No difference in expression was noted between heterozygous and homozygous embryos.
Specimen 2C: embryonic day 12.5; Hoxa13tm1.1Mrc/Hoxa13+ (more )
Structure Level Pattern Image Note
TS20: genital tubercle Present 2C
Specimen 2D: embryonic day 12.5; Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc (more )
Structure Level Pattern Image Note
TS20: genital tubercle Present 2D No difference in expression was noted between heterozygous and homozygous embryos.
Specimen 6J: embryonic day 11.5; Hoxa13tm1.1Mrc/Hoxa13+ (more )
Structure Level Pattern Image Note
TS19: genital tubercle Present 6J
Specimen 6L: embryonic day 11.5; Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc (more )
Structure Level Pattern Image Note
TS19: genital tubercle Present 6L No difference in expression was noted between heterozygous and homozygous embryos.
Specimen 7C: embryonic day 12.5; Hoxa13tm1.1Mrc/Hoxa13+ (more )
Structure Level Pattern Image Note
TS20: reproductive system Present Regionally restricted 7C Expression was detected in the urethral plate epithelium.
Specimen 7D: embryonic day 12.5; Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc (more )
Structure Level Pattern Image Note
TS20: reproductive system Present Regionally restricted 7D Expression was detected in the urethral plate epithelium and was not different from the heterozygous embryo.
Specimen 7E: embryonic day 12.5; Hoxa13tm1.1Mrc/Hoxa13+ (more )
Structure Level Pattern Image Note
TS20: reproductive system Present Regionally restricted 7E Expression was detected in the urethral plate epithelium.
Specimen 7F: embryonic day 12.5; Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc (more )
Structure Level Pattern Image Note
TS20: reproductive system Present Regionally restricted 7F Expression was detected in the urethral plate epithelium and was not different from the heterozygous embryo.
Specimen 8A: embryonic day 13.5; Hoxa13tm1.1Mrc/Hoxa13+ (more )
Note: Double labeled: green - Hoxa13 reporter; red - Pecam1 (assay MGI:2675829).
Structure Level Pattern Image Note
TS21: blood vessel Present 8A
TS21: genital tubercle of male Present 8A
Specimen 8B: embryonic day 13.5; Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc (more )
Note: Double labeled: green - Hoxa13 reporter; red - Pecam1 (assay MGI:2675829).
Structure Level Pattern Image Note
TS21: blood vessel Weak 8B
TS21: genital tubercle of male Present 8B No difference in expression was noted between heterozygous and homozygous embryos.
Specimen 9A: embryonic day 15.5; Hoxa13tm1.1Mrc/Hoxa13+ (more )
Note: Double labeled: green - Hoxa13 reporter; red - Ar (assay MGI:2675828).
Structure Level Pattern Image Note
TS23: male reproductive system Present 9A
Specimen 9B: embryonic day 15.5; Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc (more )
Note: Double labeled: green - Hoxa13 reporter; red - Ar (assay MGI:2675828).
Structure Level Pattern Image Note
TS23: male reproductive system Present 9B No difference in expression was noted between heterozygous and homozygous embryos.
Specimen 9C: embryonic day 15.5; Hoxa13tm1.1Mrc/Hoxa13+ (more )
Note: Double labeled: green - Hoxa13 reporter; red - Ar (assay MGI:2675828).
Structure Level Pattern Image Note
TS23: male reproductive system Present Regionally restricted 9C Expression was detected in the mesenchyme immediately adjacent to the urethral plate epithelium.
Specimen 9D: embryonic day 15.5; Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc (more )
Note: Double labeled: green - Hoxa13 reporter; red - Ar (assay MGI:2675828).
Structure Level Pattern Image Note
TS23: male reproductive system Present 9D No difference in expression was noted between heterozygous and homozygous embryos.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory