Gene Expression Data
Assay Details
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Assay
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Reference:
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J:83431
Morgan EA, et al., Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia. Development. 2003 Jul;130(14):3095-109
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2675821
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Gene symbol:
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Bmp7
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Gene name:
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bone morphogenetic protein 7
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Results
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Specimen
3A:
embryonic day 12.5
(more  )
Specimen
3A:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 12.5
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Sex:
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Male
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: genital tubercle |
Present |
Regionally restricted |
3A
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Expression was detected in the urethral plate epithelium and the lateral shelf mesenchyme.
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Specimen
3B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc
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Age:
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embryonic day 12.5
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Sex:
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Male
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: genital tubercle |
Present |
Regionally restricted |
3B
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Like wild type, expression was detected in the distal portion of the urethral plate epithelium (UPE). Unlike wild type, expression was not detected in the proximal UPE and was low or absent in the lateral shelf mesenchyme.
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Specimen
3C:
embryonic day 14.5
(more )
Specimen
3C:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 14.5
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Sex:
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Male
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Type:
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whole mount
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Specimen
3D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc
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Age:
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embryonic day 14.5
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Sex:
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Male
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: genital tubercle of male |
Present |
Regionally restricted |
3D
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Expression was reduced in the meatus compared to wild type and was absent from the urethral epithelium.
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| TS22: male reproductive system |
Present |
Regionally restricted |
3D
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Expression was reduced in the preputial gland compared to wild type.
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Analysis Tools
