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Gene Expression Data
Assay Details
Assay
Reference: J:41878 Zoltewicz JS, et al., oto is a homeotic locus with a role in anteroposterior development that is partially redundant with Lim1. Development. 1999 Nov;126(22):5085-95
Assay type: RNA in situ
MGI Accession ID: MGI:1346420
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Probe: Otx2 probe8
Probe preparation: RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3M: embryonic day 9.5 (more )
Note: Double labeled: magenta - Otx2; purple - Shh (assay MGI:1346421)
Structure Level Pattern Image Note
TS15: central nervous system Present Regionally restricted 3M Otx2 is expressed in anterior neurectoderm.
Specimen 3N: embryonic day 9.5; Pgap1oto/Pgap1+ (more )
Note: Severely affected oto mutant. Double labeled: magenta - Otx2; purple - Shh (assay MGI:1346421)
Structure Level Pattern Image Note
TS15: central nervous system Present Regionally restricted 3N Expression in this mutant is the same as in wild-type embryos.
Specimen 4E: embryonic day 8.0 (more )
Note: 6-8 somites.
Structure Level Pattern Image Note
TS12: future midbrain Present Uniform 4E
TS12: future prosencephalon Present Uniform 4E
Specimen 4F: embryonic day 8.0; Pgap1oto/Pgap1+ (more )
Note: 6-8 somites.
Structure Level Pattern Image Note
TS12: future midbrain Present Uniform 4F Expression in this mutant is the same as in wild-type embryos.
TS12: future prosencephalon Present Uniform 4F Expression in this mutant is the same as in wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory