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Gene Expression Data
Assay Details
Assay
Reference: J:41878 Zoltewicz JS, et al., oto is a homeotic locus with a role in anteroposterior development that is partially redundant with Lim1. Development. 1999 Nov;126(22):5085-95
Assay type: RNA in situ
MGI Accession ID: MGI:1346421
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe16
Probe preparation: RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3M: embryonic day 9.5 (more )
Note: Double labeled: purple - Shh; magenta - Otx2 (assay MGI:1346420).
Structure Level Pattern Image Note
TS15: future brain Present Regionally restricted 3M Expression is ventrally restricted but extends through the neuraxis.
Specimen 3N: embryonic day 9.5; Pgap1oto/Pgap1+ (more )
Note: Severely affected oto mutant. Double labeled: purple - Shh; magenta - Otx2 (assay MGI:1346420).
Structure Level Pattern Image Note
TS15: future brain Present Regionally restricted 3N Expression in this mutant is the same as in wild-type embryos. Expression supports the conclusion that the posterior as well as the majority of the anterior diencephalon are intact.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory