Phenotypes Associated with This Genotype

Genotype
MGI:3836175

• Allelic Composition: Rho^{tm2(RHO/GFP)Jhw}/Rho^{tm2(RHO/GFP)Jhw}
• Genetic Background: involves: 129S7/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal retina layer morphology ( J:128212 )

• thin

abnormal retina photoreceptor morphology ( J:128212 )

• the outer and inner segment boundaries are difficult to distinguish at 3, 6, and 8 weeks

abnormal photoreceptor outer segment morphology ( J:128212 )

• at 2 weeks, nascent rod outer segments exhibit non-uniform clumps unlike in wild-type mice

retina photoreceptor degeneration ( J:128212 )

thin retina outer nuclear layer ( J:128212 )

retina degeneration ( J:128212 )

• whether light/dark reared or dark-only reared

nervous system

abnormal retina photoreceptor morphology ( J:128212 )

• the outer and inner segment boundaries are difficult to distinguish at 3, 6, and 8 weeks

abnormal photoreceptor outer segment morphology ( J:128212 )

• at 2 weeks, nascent rod outer segments exhibit non-uniform clumps unlike in wild-type mice

retina photoreceptor degeneration ( J:128212 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
retinitis pigmentosa 4		DOID:0110372	OMIM:613731	J:128212