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Phenotypes Associated with This Genotype
Genotype
MGI:3655825
Allelic
Composition
Foxc1tm1Blh/Foxc1+
Tyrc-2J/Tyrc-2J
Genetic
Background
B6.Cg-Tyrc-2J Foxc1tm1Blh
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxc1tm1Blh mutation (0 available); any Foxc1 mutation (13 available)
Tyrc-2J mutation (23 available); any Tyr mutation (360 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• albino mice had severe and more extensive angle developmental defects than pigmented Foxc1tm1Blh /Foxc1+ mice
• a small or absent Schlemm's canal
• basal lamina extending from the cornea over the trabecular meshwork
• broad synechiae occupies the region where the trabecular meshwork is normally located

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
buphthalmos DOID:11211 OMIM:231300
J:82280


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/28/2023
MGI 6.22
The Jackson Laboratory