About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Nat10em1Meij
endonuclease-mediated mutation 1, Jordan L Meier
MGI:8404130
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Nat10em1Meij/Nat10em1Meij C57BL/6Cr-Nat10em1Meij/Meij MGI:8404134
cx2
Nat10em1Meij/Nat10em1Meij
Trp53tm1Tyj/Trp53+
involves: 129S2/SvPas * C57BL/6J * C57BL/6NCr MGI:8404137


Genotype
MGI:8404134
hm1
Allelic
Composition
Nat10em1Meij/Nat10em1Meij
Genetic
Background
C57BL/6Cr-Nat10em1Meij/Meij
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nat10em1Meij mutation (0 available); any Nat10 mutation (74 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• cultured blastocysts contain pyknotic nuclei and cleaved caspase-3-positive cells
• however, blastocyst form at a normal rate.

mortality/aging
• no mice are recovered at weaning




Genotype
MGI:8404137
cx2
Allelic
Composition
Nat10em1Meij/Nat10em1Meij
Trp53tm1Tyj/Trp53+
Genetic
Background
involves: 129S2/SvPas * C57BL/6J * C57BL/6NCr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nat10em1Meij mutation (0 available); any Nat10 mutation (74 available)
Trp53tm1Tyj mutation (12 available); any Trp53 mutation (248 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• no mice are recovered at weaning





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
07/08/2026
MGI 6.24
The Jackson Laboratory