All Phenotypes Bud31<em1.1Gpt> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Bud31^em1.1Gpt
endonuclease-mediated mutation 1.1, GemPharmatech
MGI:8288380

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Bud31^em1.1Gpt/Bud31^em1.1Gpt	involves: C57BL/6JGpt	MGI:8288382

Allelic Composition	Bud31^em1.1Gpt/Bud31^em1.1Gpt
Genetic Background	involves: C57BL/6JGpt

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bud31^em1.1Gpt mutation (0 available); any Bud31 mutation (18 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body size ( J:333861 )

reproductive system

decreased male germ cell number ( J:333861 )

• severe germ cell loss in the tubules

small testis ( J:333861 )

abnormal spermatogenesis ( J:333861 )

• loss of spermatogonial stem cells is first seen at P4 in the seminiferous tubules indicating defects in spermatogonial stem cell self-renewal

abnormal male meiosis ( J:333861 )

• male germ cells fail to enter meiosis

male infertility ( J:333861 )

endocrine/exocrine glands

small testis ( J:333861 )

cellular

decreased male germ cell number ( J:333861 )

• severe germ cell loss in the tubules

abnormal male meiosis ( J:333861 )

• male germ cells fail to enter meiosis

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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