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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Vangl1em1Bgao
endonuclease-mediated mutation 1, Bo Gao
MGI:8283332
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Vangl1em1Bgao/Vangl1em1Bgao C57BL/6-Vangl1em1Bgao MGI:8283340
cx2
 		Vangl1em1Bgao/Vangl1Gt(XL802)Byg
Vangl2tm1.2Yy/Vangl2+ 		involves: 129P2/OlaHsd * C57BL/6 MGI:8283342
cx3
 		Vangl1em1Bgao/Vangl1em1Bgao
Vangl2tm1.2Yy/Vangl2+ 		involves: C57BL/6 MGI:8283341


Genotype
MGI:8283340
hm1
Allelic
Composition		 Vangl1em1Bgao/Vangl1em1Bgao
Genetic
Background		 C57BL/6-Vangl1em1Bgao
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vangl1em1Bgao mutation (0 available); any Vangl1 mutation (86 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:357898 )
N
• viable

reproductive system

skeleton
skeleton phenotype ( J:357898 )
N
• normal skeletal morphology




Genotype
MGI:8283342
cx2
Allelic
Composition		 Vangl1em1Bgao/Vangl1Gt(XL802)Byg
Vangl2tm1.2Yy/Vangl2+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vangl1em1Bgao mutation (0 available); any Vangl1 mutation (86 available)
Vangl1Gt(XL802)Byg mutation (1 available); any Vangl1 mutation (86 available)
Vangl2tm1.2Yy mutation (0 available); any Vangl2 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
curly tail ( J:357898 )
• looptail in ~37% of mice

reproductive system




Genotype
MGI:8283341
cx3
Allelic
Composition		 Vangl1em1Bgao/Vangl1em1Bgao
Vangl2tm1.2Yy/Vangl2+
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vangl1em1Bgao mutation (0 available); any Vangl1 mutation (86 available)
Vangl2tm1.2Yy mutation (0 available); any Vangl2 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
caudal hemivertebra ( J:357898 )
• at age 2 months
curly tail ( J:357898 )
• looptail in ~43% of mice

skeleton
abnormal vertebrae morphology ( J:357898 )
• at age 2 months
caudal hemivertebra ( J:357898 )
• at age 2 months




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory