Phenotypes associated with this allele

• Allele Symbol: Sertm2^em1Jnch
• Allele Name: endonuclease-mediated mutation 1, Jun-An Chen
• Allele ID: MGI:8261512
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Sertm2^em1Jnch/Sertm2^em1Jnch Tg(Hlxb9-GFP)1Tmj/0	involves: C57BL/6J * CBA	MGI:8261538

Genotype
MGI:8261538

cx1

• Allelic Composition: Sertm2^em1Jnch/Sertm2^em1Jnch; Tg(Hlxb9-GFP)1Tmj/0
• Genetic Background: involves: C57BL/6J * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired coordination ( J:365477 )

• increased slippage a beam walking test and a treadmill

• alternating homologous gait

• however, mice exhibit normal homolateral limb and synchronous diagonal limb gaits

nervous system

abnormal motor neuron innervation pattern ( J:365477 )

• reduced branching of nerve latissimus dorsi with reduced coverage of the cutaneous maximus