All Phenotypes Ido2<em1Lamn> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ido2^em1Lamn
endonuclease-mediated mutation 1, Laura Mandik-Nayak
MGI:7579075

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ido2^em1Lamn/Ido2^em1Lamn	involves: BALB/c * C57BL/6J	MGI:7579161
cx2	Ido2^em1Lamn/Ido2^em1Lamn Tg(TcraR28,TcrbR28)KRNDim/0	involves: C57BL/6 * C57BL/6J * SJL	MGI:7579160

Allelic Composition	Ido2^em1Lamn/Ido2^em1Lamn
Genetic Background	involves: BALB/c * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ido2^em1Lamn mutation (0 available); any Ido2 mutation (41 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased susceptibility to type IV hypersensitivity reaction ( J:342726 )

• minimal inflammatory cell invasion and swelling after sensitizing footpads, abdomen and ears with oxazolone

Allelic Composition	Ido2^em1Lamn/Ido2^em1Lamn Tg(TcraR28,TcrbR28)KRNDim/0
Genetic Background	involves: C57BL/6 * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ido2^em1Lamn mutation (0 available); any Ido2 mutation (41 available)
Tg(TcraR28,TcrbR28)KRNDim mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

arthritis ( J:342726 )

• extensive immune cell infiltration, synovial hyperplasia and cartilage erosion

skeleton

arthritis ( J:342726 )

• extensive immune cell infiltration, synovial hyperplasia and cartilage erosion

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