All Phenotypes Rr381<em2Kap> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rr381^em2Kap
endonuclease-mediated mutation 2, Dietmar J Kappes
MGI:7439127

Summary

5 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rr381^em2Kap/Rr381^em2Kap	involves: C57BL/6	MGI:7439197
cx2	B2m^tm1Unc/B2m^tm1Unc Rr381^em2Kap/Rr381^em2Kap	involves: 129P2/OlaHsd * C57BL/6	MGI:7439201
cx3	H2^dlAb1-Ea/H2^dlAb1-Ea Rr381^em2Kap/Rr381^em2Kap	involves: 129S2/SvPas * C57BL/6	MGI:7439200
cx4	Rr381^em2Kap/Rr381^em2Kap Tg(TcraTcrb)1100Mjb/0	involves: C57BL/6	MGI:7439198
cx5	Rr381^em2Kap/Rr381^em2Kap Tg(TcrAND)53Hed/0	involves: C57BL/6 * SJL	MGI:7439199

Allelic Composition	Rr381^em2Kap/Rr381^em2Kap
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:333471 )

N	• normal single-positive (SP) CD4+ to CD8+ T cell ratio • normal proportions of SP CD8+ thymocytes and mature CD8+ T cells

Allelic Composition	B2m^tm1Unc/B2m^tm1Unc Rr381^em2Kap/Rr381^em2Kap
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
B2m^tm1Unc mutation (38 available); any B2m mutation (122 available)
Rr381^em2Kap mutation (0 available); any Rr381 mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

absent CD8-positive, alpha-beta T cells ( J:333471 )

immune system

absent CD8-positive, alpha-beta T cells ( J:333471 )

Allelic Composition	H2^dlAb1-Ea/H2^dlAb1-Ea Rr381^em2Kap/Rr381^em2Kap
Genetic Background	involves: 129S2/SvPas * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2^dlAb1-Ea mutation (13 available); any H2 mutation (280 available)
Rr381^em2Kap mutation (0 available); any Rr381 mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

absent CD4-positive, alpha-beta T cells ( J:333471 )

immune system

absent CD4-positive, alpha-beta T cells ( J:333471 )

Allelic Composition	Rr381^em2Kap/Rr381^em2Kap Tg(TcraTcrb)1100Mjb/0
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr381^em2Kap mutation (0 available); any Rr381 mutation (0 available)
Tg(TcraTcrb)1100Mjb mutation (6 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:333471 )

N	• normal MHC class-specific T cell development

Allelic Composition	Rr381^em2Kap/Rr381^em2Kap Tg(TcrAND)53Hed/0
Genetic Background	involves: C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr381^em2Kap mutation (0 available); any Rr381 mutation (0 available)
Tg(TcrAND)53Hed mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:333471 )

N	• normal MHC class-specific T cell development

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23