All Phenotypes Ptpra<tm1c(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ptpra^{tm1c(EUCOMM)Hmgu}
targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
MGI:6682153

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Ptpra^{tm1c(EUCOMM)Hmgu}/Ptpra^{tm1c(EUCOMM)Hmgu} Sftpc^{tm1(cre/ERT2)Blh}/Sftpc⁺	involves: 129S6/SvEvTac * C57BL/6N	MGI:6690444
cn2	Ptpra^{tm1c(EUCOMM)Hmgu}/Ptpra^{tm1c(EUCOMM)Hmgu} Twist2^{tm1.1(cre)Dor}/Twist2⁺	involves: 129X1/SvJ * C57BL/6N	MGI:6690443

Allelic Composition	Ptpra^{tm1c(EUCOMM)Hmgu}/Ptpra^{tm1c(EUCOMM)Hmgu} Sftpc^{tm1(cre/ERT2)Blh}/Sftpc⁺
Genetic Background	involves: 129S6/SvEvTac * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptpra^{tm1c(EUCOMM)Hmgu} mutation (0 available); any Ptpra mutation (45 available)
Sftpc^{tm1(cre/ERT2)Blh} mutation (1 available); any Sftpc mutation (23 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:300194 )

N	• bleomycin, tamoxifen-treated mice develop fibrosis and lung collagen content as in control mice

Allelic Composition	Ptpra^{tm1c(EUCOMM)Hmgu}/Ptpra^{tm1c(EUCOMM)Hmgu} Twist2^{tm1.1(cre)Dor}/Twist2⁺
Genetic Background	involves: 129X1/SvJ * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptpra^{tm1c(EUCOMM)Hmgu} mutation (0 available); any Ptpra mutation (45 available)
Twist2^{tm1.1(cre)Dor} mutation (1 available); any Twist2 mutation (10 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

decreased susceptibility to injury ( J:300194 )

• bleomycin-treated mice are protected from pulmonary fibrosis

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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