About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ythdf3em2Jhha
endonuclease-mediated mutation 2, Jacob Hanna
MGI:6491619
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ythdf3em2Jhha/Ythdf3em2Jhha involves: BALB/c * C57BL/6 MGI:6491913
cx2
 		Ythdf1em2Jhha/Ythdf1em2Jhha
Ythdf2em2Jhha/Ythdf2em2Jhha
Ythdf3em2Jhha/Ythdf3em2Jhha 		involves: BALB/c * C57BL/6 MGI:6491914
cx3
 		Ythdf1em2Jhha/Ythdf1em2Jhha
Ythdf2em2Jhha/Ythdf2+
Ythdf3em2Jhha/Ythdf3em2Jhha 		involves: BALB/c * C57BL/6 MGI:6491915
cx4
 		Ythdf1em2Jhha/Ythdf1em2Jhha
Ythdf2em2Jhha/Ythdf2+
Ythdf3em2Jhha/Ythdf3+ 		involves: BALB/c * C57BL/6 MGI:6491916
cx5
 		Ythdf1em2Jhha/Ythdf1+
Ythdf2em2Jhha/Ythdf2+
Ythdf3em2Jhha/Ythdf3em2Jhha 		involves: BALB/c * C57BL/6 MGI:6491917


Genotype
MGI:6491913
hm1
Allelic
Composition		 Ythdf3em2Jhha/Ythdf3em2Jhha
Genetic
Background		 involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ythdf3em2Jhha mutation (0 available); any Ythdf3 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:299108 )
N
• born at expected mendelian ratio

mortality/aging
mortality/aging ( J:299108 )
N
• viable; born at expected mendelian ratio

reproductive system




Genotype
MGI:6491914
cx2
Allelic
Composition		 Ythdf1em2Jhha/Ythdf1em2Jhha
Ythdf2em2Jhha/Ythdf2em2Jhha
Ythdf3em2Jhha/Ythdf3em2Jhha
Genetic
Background		 involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ythdf1em2Jhha mutation (0 available); any Ythdf1 mutation (35 available)
Ythdf2em2Jhha mutation (0 available); any Ythdf2 mutation (32 available)
Ythdf3em2Jhha mutation (0 available); any Ythdf3 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:6491915
cx3
Allelic
Composition		 Ythdf1em2Jhha/Ythdf1em2Jhha
Ythdf2em2Jhha/Ythdf2+
Ythdf3em2Jhha/Ythdf3em2Jhha
Genetic
Background		 involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ythdf1em2Jhha mutation (0 available); any Ythdf1 mutation (35 available)
Ythdf2em2Jhha mutation (0 available); any Ythdf2 mutation (32 available)
Ythdf3em2Jhha mutation (0 available); any Ythdf3 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:6491916
cx4
Allelic
Composition		 Ythdf1em2Jhha/Ythdf1em2Jhha
Ythdf2em2Jhha/Ythdf2+
Ythdf3em2Jhha/Ythdf3+
Genetic
Background		 involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ythdf1em2Jhha mutation (0 available); any Ythdf1 mutation (35 available)
Ythdf2em2Jhha mutation (0 available); any Ythdf2 mutation (32 available)
Ythdf3em2Jhha mutation (0 available); any Ythdf3 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:299108 )
• mice born at lower than expected Mendelian ratio




Genotype
MGI:6491917
cx5
Allelic
Composition		 Ythdf1em2Jhha/Ythdf1+
Ythdf2em2Jhha/Ythdf2+
Ythdf3em2Jhha/Ythdf3em2Jhha
Genetic
Background		 involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ythdf1em2Jhha mutation (0 available); any Ythdf1 mutation (35 available)
Ythdf2em2Jhha mutation (0 available); any Ythdf2 mutation (32 available)
Ythdf3em2Jhha mutation (0 available); any Ythdf3 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:299108 )
• mice born at lower than expected Mendelian ratio




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory